The Role of the Rate of Force Application in Responses to Spinal Manipulation Therapy

NCT02550132 | Completed Results

• 1 other identifier: UQTR-2013-SMTrate
• Study Type: interventional
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

The objective of the present study is to determine if spinal manipulations with a constant rate of force application but with different peak force and time to peak force lead to similar responses in healthy adults.

Conditions

Spinal Manipulation

Keywords

electromyography; biomechanical phenomena; dose-response relationship; musculoskeletal manipulations; spinal manipulation

Outcome Measures

Primary Outcomes (28)

• Left T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Left T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T6 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Right T8 Normalized Root Mean Square (RMS) Value

  Normalized amplitude (RMS) of surface electromyography response. The normalisation was achieved by dividing the obtained RMS by the RMS value before thrust application.

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Sixth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Seventh Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Eighth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 150N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Sixth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Seventh Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Eighth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 200N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Sixth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Seventh Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Eighth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 250N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Sixth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Seventh Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

• Vertebral Displacement of the Eighth Thoracic Vertebra

  Absolute posterior to anterior vertebral displacement during the spinal manipulation in centimeter

  During the 300N spinal manipulation procedure, assessed up to 2 seconds following thrust onset

Study Arms (1)

Participants

EXPERIMENTAL

All volunteers will participate in an experimental session. Participants will be delivered four different spinal manipulations (SMT) at T7 with a rate of force application of about 2200 Newtons/seconds and a preload force of 25 Newtons (N). SMTs will differed in their time to peak force (ms) and peak force (N), respectively fixed as follow for each applied SMT: (1)57 ms / 150 N, (2)80 ms / 200 N, (3)102 ms / 250 N and (4)125 ms / 300 N.

Procedure: Spinal manipulation; Device: Apparatus used to deliver spinal manipulations

Interventions

Spinal manipulation PROCEDURE

Participants will lie down during the 45-minute experimental session. Vertebral displacements (cm) and muscle response amplitude (RMS value) will be recorded through kinematic markers (on T6, T7 and T8 spinous processes) and surface electromyography electrodes (on the left and right erector spinae at T6 and T8 vertebra level). Each SMT (4 per participant) will be delivered at T7 transverse processes by an apparatus. Responses during the thrust phase (duration equal to twice the time to peak force) and after the thrust (1,5s duration) will be compared between SMTs.

Also known as: Manual therapy

Participants

Apparatus used to deliver spinal manipulations DEVICE

An apparatus using a servo-controlled linear actuator motor (Linear Motor Series P01-48x360, LinMot Inc., Switzerland) will be used to deliver spinal manipulations.

Participants

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy adult

You may not qualify if:

• Thoracic or lumbar pain
• History of back trauma or surgery
• Severe osteoarthritis
• Inflammatory arthritis
• Vascular conditions
• Contraindication to the use of SMT

Sponsors & Collaborators

• Université du Québec à Trois-Rivières: lead
• Fondation Chiropratique du Québec: collaborator

Related Publications (1)

• Nougarou F, Page I, Loranger M, Dugas C, Descarreaux M. Neuromechanical response to spinal manipulation therapy: effects of a constant rate of force application. BMC Complement Altern Med. 2016 Jun 2;16:161. doi: 10.1186/s12906-016-1153-6.

  PMID: 27249939 DERIVED

MeSH Terms

Interventions

Manipulation, Spinal; Musculoskeletal Manipulations

Intervention Hierarchy (Ancestors)

Physical Therapy Modalities; Therapeutics; Rehabilitation; Complementary Therapies

Results Point of Contact

• Title: Dr Martin Descarreaux DC, PhD
• Organization: Université du Québec à Trois-Rivières

martin.descarreaux@uqtr.ca

18193765011

Study Officials

• Martin Descarreaux, DC, PhD

  Université du Québec à Trois-Rivières

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr Martin Descarreaux DC, PhD

Study Record Dates

• First Submitted: September 8, 2015
• First Posted: September 15, 2015
• Study Start: June 1, 2013
• Primary Completion: June 1, 2014
• Study Completion: June 1, 2014
• Last Updated: February 5, 2016
• Results First Posted: February 5, 2016

Record last verified: 2016-01