Additive Effects of Combined Spinal Manipulations on Pain Pressure Threshold

NCT02828501 | Completed

• 1 other identifier: Pro00043661
• Study Type: interventional
• Target: 57
• Locations: 0 countries
• Sites: N/A

Brief Summary

Physical therapists frequently use spinal manipulation therapy (SMT) to treat spinal pain. However, the methods by which SMT exerts its effects are not well understood. The aim of this study is to assess potential changes in pain pressure threshold following both a cervical and lumbar spine manipulation in a single treatment session at sites local and diffuse to the site of manipulation application. This study will also attempt to determine if the order of the cervical and lumbar manipulation application impacts pain pressure threshold changes.

Conditions

Pain Threshold

Keywords

Pain Threshold

Outcome Measures

Primary Outcomes (1)

• Pressure-Pain Threshold as assessed by a pressure algometer

  Two minutes

Study Arms (3)

Lumbar manipulation group

EXPERIMENTAL

Spinal Manipulation

Procedure: Spinal Manipulation

Cervical manipulation group

EXPERIMENTAL

Spinal Manipulation

Procedure: Spinal Manipulation

Control group

NO INTERVENTION

This group will receive a 2 minute supine rest between measurements

Interventions

Spinal Manipulation PROCEDURE

A spinal manipulation is a high velocity, low amplitude thrust through a physiological barrier in order to elicit a cavitation.

Cervical manipulation group; Lumbar manipulation group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• To be included in this study, consenting male and female participants must be between the ages of 18 and 60. This age range insures skeletal maturity with a reasonably low prevalence of severe osteoarthritis or osteopenia.

You may not qualify if:

• The presence of any of the following factors will exclude the participant from this study:
• Currently involved in a worker's compensation claim or in personal injury litigation.
• Currently on, or applying for, permanent or temporary disability due to a medical or mental health condition.
• Currently taking prescription analgesics.
• Activity-limiting pain arising from any site other than listed in the specific entry criteria.
• pregnancy or have been pregnant in the last year;
• spinal osteoporosis or osteopenia;
• inflammatory joint disease;
• an infection involving the spine;
• severe arthritis;
• any current (within 5 years) neoplastic condition;
• any history of vertebral fracture with current bony instability or measurable deformity;
• severe lumbar stenosis (defined as an A-P diameter of the thecal sac of less than 5 mm at any level, from mid-sagittal lumbar T2-weighted MRI);
• diagnosis of cervical spinal stenosis
• any abnormalities or compression of the spinal cord, cauda equine, or spinal nerves;

Sponsors & Collaborators

• University of South Carolina: lead

Related Publications (1)

• Jordon MK, Beattie PF, D'Urso S, Scriven S. Spinal manipulation does not affect pressure pain thresholds in the absence of neuromodulators: a randomized controlled trial. J Man Manip Ther. 2017 Sep;25(4):172-181. doi: 10.1080/10669817.2016.1230352. Epub 2016 Sep 12.

  PMID: 28912629 DERIVED

MeSH Terms

Interventions

Manipulation, Spinal

Intervention Hierarchy (Ancestors)

Musculoskeletal Manipulations; Physical Therapy Modalities; Therapeutics; Rehabilitation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD Candidate

Study Record Dates

• First Submitted: June 22, 2016
• First Posted: July 11, 2016
• Study Start: March 1, 2015
• Primary Completion: February 1, 2016
• Study Completion: February 1, 2016
• Last Updated: April 30, 2019

Record last verified: 2019-04

Data Sharing

• IPD Sharing: Will not share