Absorption and Muscle-stimulating Effect of Hydrolyzed and Minced Beef
1 other identifier
interventional
10
1 country
1
Brief Summary
To measure the absorption kinetics and postprandial amino acid availability after ingestion of minced beef compared with hydrolyzed beef in young males. Moreover, the basal muscle protein synthesis and the postprandial muscle protein synthetic response to minced beef and hydrolyzed beef ingestion are measured in young males. The postprandial muscle protein synthetic response is measured and compared during the early postprandial period (0-3 hours) after ingestion of the two meat products.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2016
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 30, 2016
CompletedFirst Posted
Study publicly available on registry
April 8, 2016
CompletedStudy Start
First participant enrolled
November 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2018
CompletedNovember 8, 2016
November 1, 2016
1.3 years
March 30, 2016
November 7, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Change in skeletal muscle protein fractional synthetic rate
The fractional synthetic rate of skeletal muscle proteins (%/h) measured during the overnight fasted state and the postprandial state.
During the postprandial period (0-3 hrs).
Secondary Outcomes (2)
Protein absorption
During the postprandial period (0-3 hrs).
Plasma amino acid concentration
During the postprandial period (0-3 hrs).
Study Arms (2)
Minced beef
ACTIVE COMPARATORMinced beef
Hydrolyzed beef
EXPERIMENTALHydrolyzed beef
Interventions
Eligibility Criteria
You may qualify if:
- Healthy
- Non-obese (BMI\<30)
You may not qualify if:
- Chronic medical disease
- \>5 hour of exercise weekly, except light activities such as stretching/gymnastics and bike-riding/walking as transportation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bispebjerg Hospital
Copenhagen NV, 2400, Denmark
Study Officials
- PRINCIPAL INVESTIGATOR
Kasper Dideriksen, PhD
Bispebjerg Hospital
- PRINCIPAL INVESTIGATOR
Lars Holm, PhD
Bispebjerg Hospital
- PRINCIPAL INVESTIGATOR
Søren Reitelseder, PhD
Bispebjerg Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- PhD, Post doc
Study Record Dates
First Submitted
March 30, 2016
First Posted
April 8, 2016
Study Start
November 1, 2016
Primary Completion
March 1, 2018
Study Completion
March 1, 2018
Last Updated
November 8, 2016
Record last verified: 2016-11
Data Sharing
- IPD Sharing
- Will not share