Isometric Handgrip Exercise for Blood Pressure Management

NCT02458456 | Completed

• 1 other identifier: UNewEngland1
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this project is to conduct a randomised controlled trial to assess the effect of performing isometric exercise using a handgrip dynamometer on blood pressure.

Conditions

Hypertension

Outcome Measures

Primary Outcomes (1)

• Change in systolic and diastolic blood pressure

  Baseline and 8 weeks

Secondary Outcomes (2)

• Compare and contrast changes in blood pressure between the 5% maximum voluntary contraction (MVC) and 30% MVC hypertensive groups

  Baseline and 8 weeks

• Compare and contrast blood pressure changes between the 30% maximum voluntary contraction (MVC) hypertensive and 30% MVC normotensive groups

  Baseline and 8 weeks

Study Arms (6)

IHG 5% Hypertensive

SHAM COMPARATOR

Participants who are either un-medicated pre-hypertensive or medicated for blood pressure management conducting isometric resistance training using a hand dynamometer at 5% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

IHG 30% Hypertensive

EXPERIMENTAL

Participants who are either un-medicated pre-hypertensive or medicated for blood pressure management conducting isometric resistance training using a hand dynamometer at 30% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

IHG 30% Normotensive

EXPERIMENTAL

Participants who are normotensive conducting isometric resistance training using a hand dynamometer at 30% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

IHG 5% Normotensive

SHAM COMPARATOR

Participants who are normotensive conducting isometric resistance training using a hand dynamometer at 5% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

IHG 10% Hypertensive

EXPERIMENTAL

Participants who are either un-medicated pre-hypertensive or medicated for blood pressure management conducting isometric resistance training using a hand dynamometer at 10% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

IHG 10% Normotensive

EXPERIMENTAL

Participants who are normotensive conducting isometric resistance training using a hand dynamometer at 10% of their maximum voluntary contraction. Participants with perform 4 x 2 minutes isometric handgrip exercises 3 times per week under supervision for 8 weeks.

Other: Isometric resistance training

Interventions

Isometric resistance training OTHER

Isometric exercise using a hand dynamometer.

IHG 10% Hypertensive; IHG 10% Normotensive; IHG 30% Hypertensive; IHG 30% Normotensive; IHG 5% Hypertensive; IHG 5% Normotensive

Eligibility Criteria

• Age: 30 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Those within the required age limits, both normotensive, pre-hypertensive, and those medicated for blood pressure management.

You may not qualify if:

• Younger than 30 years and older than 70 years; those deemed not to have the capacity to voluntarily participate, unable to participate under their doctor's recommendation, or with arthritis or carpal tunnel syndrome who may aggravate their condition with handgrip exercise.

Sponsors & Collaborators

• University of New England, Australia: lead

Study Sites (1)

University of New England

Armidale, New South Wales, 2351, Australia

Location

Related Publications (1)

• Carlson DJ, Dieberg G, Hess NC, Millar PJ, Smart NA. Isometric exercise training for blood pressure management: a systematic review and meta-analysis. Mayo Clin Proc. 2014 Mar;89(3):327-34. doi: 10.1016/j.mayocp.2013.10.030.

  PMID: 24582191 BACKGROUND

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Neil Smart, PhD

  University of New England

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Sponsor-Investigator

Study Record Dates

• First Submitted: May 21, 2015
• First Posted: June 1, 2015
• Study Start: August 1, 2014
• Primary Completion: November 1, 2016
• Study Completion: December 1, 2016
• Last Updated: December 17, 2020

Record last verified: 2020-12

Locations

AU (1)