Strength Training Study for Survivors of Breast and Gynecologic Cancer

NCT01709175 | Completed

• 1 other identifier: JB-007
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to compare once-a-week vs. twice-a-week strength training in survivors of breast and gynecologic cancer to determine which is the optimal exercise prescription.

Conditions

Breast Cancer; Gynecologic Cancer; Ovarian Cancer; Uterine Cancer; Cervical Cancer

Keywords

Cancer; Breast Cancer; Gynecologic Cancer; Strength Training; Exercise; Physical Activity; Fatigue; Quality of Life; Strength; Fitness; Cancer Survivor; Survivor

Outcome Measures

Primary Outcomes (1)

• Changes in Muscular Strength

  Muscular Strength will be assessed using the predicted one-repetition maximum method (Brzycki method)using the bench press and leg press to measure upper and lower body strength.

  Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

Secondary Outcomes (6)

• Process Measures

  Final (end of week 13)

• Changes in Muscular Endurance

  Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

• Changes in Body Composition

  Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

• Changes in Quality of Life

  Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

• Changes in Fatigue

  Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

Study Arms (2)

Once-a-week Strength Training

EXPERIMENTAL

After completing the introduction to strength training (two sessions in the first week), participants randomized to the once-a-week group will receive 12 additional weeks of progressive strength training. Participants will meet ONCE-A-WEEK to strength train in a supervised exercise group. The program includes nine exercises.

Behavioral: Strength Training

Twice-a-week Strength Training

EXPERIMENTAL

After completing the introduction to strength training (two sessions in the first week), participants randomized to the twice-a-week group will receive 12 additional weeks of progressive strength training. Participants will meet TWICE-A-WEEK to strength train in a supervised exercise group. The program includes nine exercises.

Behavioral: Strength Training

Interventions

Strength Training BEHAVIORAL

This is a 13 week strength training program. Sessions will be supervised by a Certified Exercise Physiologist in a group setting.

Also known as: Resistance Exercise, Weight Training, Body Building, Exercise, Physical Activity, Restive Exercise

Once-a-week Strength Training; Twice-a-week Strength Training

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female Survivor of Breast or Gynecologic Cancer
• Completed Primary Treatment (hormone treatments are ok)
• years of age or older
• Physician's Permission to Participate

You may not qualify if:

• High Risk Individuals (determined by questionnaire)
• Secondary Health Problems that could increase the risk of participating (Includes but not limited to: Uncontrolled angina/hypertension, heart failure, osteoporosis, brain metastases, history of seizures).
• Report participating in a strength training program in the past six (6) months
• Have had a change in medication in the past 30 days

Sponsors & Collaborators

• Nova Scotia Health Authority: lead
• Dalhousie University: collaborator

Study Sites (1)

Exercise Lab: Queen Elizabeth II Dickson Centre

Halifax, Nova Scotia, Canada

Location

MeSH Terms

Conditions

Breast Neoplasms; Ovarian Neoplasms; Uterine Neoplasms; Uterine Cervical Neoplasms; Neoplasms; Motor Activity; Fatigue

Interventions

Resistance Training; Somatotypes; Exercise

Condition Hierarchy (Ancestors)

Neoplasms by Site; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Endocrine Gland Neoplasms; Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Neoplasms, Female; Urogenital Neoplasms; Genital Diseases; Endocrine System Diseases; Gonadal Disorders; Uterine Diseases; Uterine Cervical Diseases; Behavior; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Physical Appearance, Body; Body Constitution; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Physiological Phenomena

Study Officials

• Scott Grandy, Ph D

  CDHA

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: October 9, 2012
• First Posted: October 18, 2012
• Study Start: November 1, 2012
• Primary Completion: January 1, 2015
• Study Completion: January 1, 2015
• Last Updated: June 8, 2015

Record last verified: 2015-06

Locations

CA (1)