Key Insights

Highlights

Success Rate

79% trial completion

Published Results

303 trials with published results (15%)

Research Maturity

913 completed trials (45% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.7%

239 terminated out of 2038 trials

Success Rate

79.3%

-7.3% vs benchmark

Late-Stage Pipeline

8%

169 trials in Phase 3/4

Results Transparency

33%

303 of 913 completed with results

Key Signals

303 with results79% success239 terminated

Data Visualizations

Phase Distribution

1,623Total
Not Applicable (275)
Early P 1 (24)
P 1 (611)
P 2 (544)
P 3 (149)
P 4 (20)

Trial Status

Completed913
Recruiting342
Unknown273
Terminated239
Active Not Recruiting121
Not Yet Recruiting74

Trial Success Rate

79.3%

Benchmark: 86.5%

Based on 913 completed trials

Clinical Trials (2038)

Showing 20 of 20 trials
NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT07318558Phase 3Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

NCT06824467Phase 3RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

NCT02759588Phase 1CompletedPrimary

Olvi-Vec Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

NCT04421963Phase 3Active Not RecruitingPrimary

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

NCT07638410Not ApplicableNot Yet Recruiting

Prehabilitation in High-risk Oncologic Surgery

NCT06276491Phase 1RecruitingPrimary

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

NCT07642791Not ApplicableActive Not RecruitingPrimary

Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy.

NCT07517198Phase 1Recruiting

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

NCT07610798Phase 1Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations

NCT07639801Not ApplicableNot Yet Recruiting

68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors

NCT05877599Phase 1Recruiting

A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

NCT07637851Phase 1Not Yet RecruitingPrimary

Safety and Efficacy of Ubamatamab With First-line Chemotherapy in Ovarian Cancer

NCT06695845Phase 2Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT07524322Phase 1Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

NCT07059845Phase 2RecruitingPrimary

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

NCT07634094Phase 2Not Yet RecruitingPrimary

Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer

NCT04931342Phase 2Active Not RecruitingPrimary

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

NCT00043472Completed

Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

NCT05964361Phase 1Completed

First-in-human Interleukin-15-transpresenting Wilms' Tumor Protein 1-targeting Autologous Dendritic Cell Vaccination in Cancer Patients

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