Key Insights

Highlights

Success Rate

79% trial completion

Published Results

311 trials with published results (15%)

Research Maturity

920 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.8%

243 terminated out of 2068 trials

Success Rate

79.1%

-7.4% vs benchmark

Late-Stage Pipeline

8%

170 trials in Phase 3/4

Results Transparency

34%

311 of 920 completed with results

Key Signals

311 with results79% success243 terminated

Data Visualizations

Phase Distribution

1,645Total
Not Applicable (280)
Early P 1 (26)
P 1 (620)
P 2 (549)
P 3 (150)
P 4 (20)

Trial Status

Completed920
Recruiting350
Unknown270
Terminated243
Active Not Recruiting120
Not Yet Recruiting87

Trial Success Rate

79.1%

Benchmark: 86.6%

Based on 920 completed trials

Clinical Trials (2068)

Showing 20 of 20 trials
NCT07318558Phase 3Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

NCT06253520Phase 1Active Not Recruiting

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

NCT06824467Phase 3RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

NCT03412877Phase 2Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

NCT07593092Phase 1RecruitingPrimary

Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors

NCT02830724Phase 1Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

NCT05489211Phase 2Recruiting

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

NCT07042802Phase 1RecruitingPrimary

A Study of LBL-024 in Combination With Paclitaxel ± Bevacizumab for the Treatment of Platinum-resistant Ovarian Cancer

NCT06040970Phase 1RecruitingPrimary

Sacituzumab Govitecan in Combination With Cisplatin in Platinum Sensitive Recurrent Ovarian and Endometrial Cancer

NCT06399757Phase 1Active Not Recruiting

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

NCT05572684Phase 1Terminated

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

NCT00043472Completed

Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

NCT06840886Phase 1Recruiting

A Study of PHST001 in Advanced Solid Tumors

NCT07761416Early Phase 1Not Yet RecruitingPrimary

Opportunistic Salpingectomy During Bariatric Surgery for Ovarian Cancer Prevention

NCT04354246Phase 1Completed

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

NCT04044859Phase 1Active Not Recruiting

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

NCT06851429RecruitingPrimary

Ovarian Cancer Identification on CT Using Deep Learning

NCT07760012Not ApplicableRecruiting

68Ga-SorB PET/CT Imaging in Patients With Solid Tumors

NCT07546500Phase 3RecruitingPrimary

A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

NCT06787612Phase 2RecruitingPrimary

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

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Research Network

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