STERK - Strength Training and Eating Disorders

NCT02142439 | Completed

• 1 other identifier: STERK
• Study Type: interventional
• Target: 6
• Locations: 1 country
• Sites: 3

Brief Summary

Strength training has been found effective for enhancement of bone health, muscle strength and body composition among premenopausal women from the general population, however it is unclear to what extend strength training might improve these parameters among women with eating disorders. The aim of this study is therefore to examine acute and long-term effects of strength training among persons with eating disorders. The study is a randomized, controlled, single-blinded trial with three intervention groups and one control group. The three intervention groups will perform different volumes of strength training. The intervention period is 16 weeks with three sessions per week. At pretest, posttest, and 6 months, 12 months and 24 months follow-up, the following variables will be measured: bone health, muscle strength, power, body composition hormone levels, physical activity level and compulsivity, body awareness, quality of life, and eating disorders psychopathology. Qualitative in-depth interviews will be carried out to explore the participants' experiences with strength training. The study is carried out in Norway, and is performed in collaboration with Telemark University College, University of Agder, Norwegian school of sport sciences and Modum Bad psychiatric center. The results from the study might implicate on strength training as part of treatment for eating disorders.

Conditions

Eating Disorders

Keywords

Anorexia; Bulimia; Physical activity; Treatment

Outcome Measures

Primary Outcomes (1)

• Bone mineral density (DXA)

  up to two years follow-up

Secondary Outcomes (8)

• 1RM squats

  16 weeks, two years follow-up

• 1RM bench press

  16 weeks, two years follow-up

• Eating Disorders Examination clinical interview

  16 weeks, two years follow-up

• DXA

  16 weeks, two years follow-up

• Self-reported physical activity behavior

  16 weeks, two years follow-up

Other Outcomes (3)

• Body attitude

  16 weeks, two years follow-up

• Short Form - 36

  16 weeks, two years follow-up

• Participants' experience with strength training

  16 weeks

Study Arms (4)

Intervention group 1

EXPERIMENTAL

Exercise counseling 1 time/week, Strength training 3 times/week, dose: 5 RM x 3 sets.

Behavioral: Strength training

Intervention group 2

EXPERIMENTAL

Exercise counseling 1 time/week. Strength training 3 times/week, dose: 10 RM x 3 sets.

Behavioral: Strength training

Intervention group 3

EXPERIMENTAL

Exercise counseling 1 time/week. Strength training 3 times/week, dose: 30 RM x 3 sets

Behavioral: Strength training

Control group

NO INTERVENTION

Exercise counseling 1 time/week

Interventions

Strength training BEHAVIORAL

Three times per week with strength training

Intervention group 1; Intervention group 2; Intervention group 3

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Meeting diagnostic criteria for anorexia nervosa, bulimia nervosa or eating disorders not otherwise specified
• Outpatient/home-dwelling
• Age: 18 years or older
• Premenopausal women

You may not qualify if:

• BMI \<15 kg/m2
• Osteoporosis (t-score \< -2,5 including low energy fracture)
• Psychosis, suicidal behavior
• Planned changes in medication during the 16 weeks of intervention
• Planned pregnancy within the 16 weeks intervention period, and/or up to one year follow-up (due to DXA scanning)

Sponsors & Collaborators

• University of South-Eastern Norway: lead
• University of Agder: collaborator
• Norwegian School of Sport Sciences: collaborator
• Modum Bad: collaborator

Study Sites (3)

University of Agder

Kristiansand, Agder, Norway

Location

Telemark University College

Bø, Telemark, 3800, Norway

Location

Norwegian school of sport sciences

Oslo, Norway

Location

Related Publications (7)

• Shroff H, Reba L, Thornton LM, Tozzi F, Klump KL, Berrettini WH, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel P, LaVia M, Mitchell J, Rotondo A, Strober M, Treasure J, Woodside DB, Kaye WH, Bulik CM. Features associated with excessive exercise in women with eating disorders. Int J Eat Disord. 2006 Sep;39(6):454-61. doi: 10.1002/eat.20247.

  PMID: 16637047 BACKGROUND

• Mehler PS, Cleary BS, Gaudiani JL. Osteoporosis in anorexia nervosa. Eat Disord. 2011 Mar-Apr;19(2):194-202. doi: 10.1080/10640266.2011.551636.

  PMID: 21360368 BACKGROUND

• Grinspoon S, Thomas E, Pitts S, Gross E, Mickley D, Miller K, Herzog D, Klibanski A. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann Intern Med. 2000 Nov 21;133(10):790-4. doi: 10.7326/0003-4819-133-10-200011210-00011.

  PMID: 11085841 BACKGROUND

• Borer KT. Physical activity in the prevention and amelioration of osteoporosis in women : interaction of mechanical, hormonal and dietary factors. Sports Med. 2005;35(9):779-830. doi: 10.2165/00007256-200535090-00004.

  PMID: 16138787 BACKGROUND

• Mosti MP, Kaehler N, Stunes AK, Hoff J, Syversen U. Maximal strength training in postmenopausal women with osteoporosis or osteopenia. J Strength Cond Res. 2013 Oct;27(10):2879-86. doi: 10.1519/JSC.0b013e318280d4e2.

  PMID: 23287836 BACKGROUND

• Szabo CP, Green K. Hospitalized anorexics and resistance training: impact on body composition and psychological well-being. A preliminary study. Eat Weight Disord. 2002 Dec;7(4):293-7. doi: 10.1007/BF03324975.

  PMID: 12588057 BACKGROUND

• Chantler I, Szabo CP, Green K. Muscular strength changes in hospitalized anorexic patients after an eight week resistance training program. Int J Sports Med. 2006 Aug;27(8):660-5. doi: 10.1055/s-2005-865812.

  PMID: 16874594 BACKGROUND

MeSH Terms

Conditions

Feeding and Eating Disorders; Anorexia; Bulimia; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders; Hyperphagia; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Solfrid Bratland-Sanda, PhD

  University of South-Eastern Norway

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2014
• First Posted: May 20, 2014
• Study Start: January 1, 2014
• Primary Completion: December 1, 2019
• Study Completion: December 1, 2019
• Last Updated: March 26, 2020

Record last verified: 2020-03

Data Sharing

• IPD Sharing: Will not share

Locations

NO (3)