NCT01216774

Brief Summary

The purpose of this study is to compare the impact of different levels of mechanical stress and muscle fatigue in strength training conditions on muscle strength, muscle mass and inflammatory processes.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2010

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 6, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 7, 2010

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
Last Updated

June 18, 2012

Status Verified

September 1, 2010

Enrollment Period

3 months

First QC Date

October 6, 2010

Last Update Submit

June 15, 2012

Conditions

Strength TrainingMuscle Strength, Muscle Mass, Inflammatory Processes

Outcome Measures

Primary Outcomes (1)

  • Force-velocity characteristics of knee extensors with biodex dynamometer

    Pre and post intervention

Study Arms (3)

Low load + fatigue

EXPERIMENTAL
Other: Strength training

High load

ACTIVE COMPARATOR
Other: Strength training

Low load

PLACEBO COMPARATOR
Other: Strength training

Interventions

Strength trainingOTHER

Leg extension exercise: Experimental: 60 repetitions at 20-25% of 1RM, 10-12 repetitions at 40% of 1RM Active Comparator: 10-12 repetitions at 80% of 1RM Placebo Comparator: 10-12 repetitions at 40% of 1RM

High loadLow loadLow load + fatigue

Eligibility Criteria

Age20 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may not qualify if:

  • Knee pathology
  • Systematic training

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Kinesiology and Rehabilitation Sciences

Leuven, Leuven, 3001, Belgium

Location

MeSH Terms

Interventions

Resistance Training

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 6, 2010

First Posted

October 7, 2010

Study Start

September 1, 2010

Primary Completion

December 1, 2010

Last Updated

June 18, 2012

Record last verified: 2010-09

Locations

BE(1)