Health Benefits of Chronic vs. Acute Exercise in Overweight Adults
2 other identifiers
interventional
43
1 country
1
Brief Summary
Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable obesity
Started May 2009
Longer than P75 for not_applicable obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2009
CompletedFirst Submitted
Initial submission to the registry
October 11, 2011
CompletedFirst Posted
Study publicly available on registry
October 14, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2014
CompletedNovember 24, 2014
November 1, 2014
4.8 years
October 11, 2011
November 20, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
oral glucose tolerance test
2 hour
Secondary Outcomes (1)
Resting Metabolic Rate
20-30 min
Study Arms (1)
Exercise Session
OTHERSubjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).
Interventions
Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).
Eligibility Criteria
You may qualify if:
- Body Mass Index: 27-34 kg/m2;
- Regular exercisers(≥4 days/wk of aerobic exercise;
- min/session at moderate and vigorous intensities);
- Non-exercisers (no regularly planned exercise/physical activity);
- Women must have regularly occurring menses and must be premenopausal.
You may not qualify if:
- Pregnant or lactating;
- Evidence/history of cardiovascular or metabolic disease;
- Currently taking medications known to affect lipid or glucose metabolism.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Substrate Metabolism Laboratory
Ann Arbor, Michigan, 48109, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jeffrey F Horowitz, Ph.D.
University of Michigan
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor, Movement Science, School of Kinesiology
Study Record Dates
First Submitted
October 11, 2011
First Posted
October 14, 2011
Study Start
May 1, 2009
Primary Completion
February 1, 2014
Study Completion
October 1, 2014
Last Updated
November 24, 2014
Record last verified: 2014-11