Investigator left site
CisPemXetSrg
A Phase I Trial of Preoperative Carboplatin or Cisplatin and Pemetrexed With Thoracic Radiation Therapy Followed by Lobectomy in Resectable Stage III Patients With Non-Squamous Non Small Cell Lung Cancer (NSCLC)
Sponsor study identifier
interventional
48
1 country
1
Study Start
May 2011
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
June 2012
Actual (reported)Study Completion
June 2012
Actual (reported)This study is open to patients that have been diagnosed with non-squamous Stage III Non Small Cell Lung Cancer (NSCLC) and will have surgery to remove the tumor. The purpose of this study is to:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2012
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2011
Date type not reportedThis date has not been verified as actual or estimated.
June 13, 2011
Actual (reported)June 15, 2011
Actual (reported)June 2012
Actual (reported)June 2012
Actual (reported)Safety and tolerability
Determine the safety and tolerability of concurrent chemotherapy with Cisplatin/ Pemetrexed or Carboplatin/Pemetrexed and dose escalated radiation therapy followed by lobectomy.
Response rate, overall survival and progression free survival
1. Patients will be given the drugs pemetrexed and carboplatin 2. Radiation 3. Participants evaluated for response 4. Lobectomy surgery
1. Patients will be given the drugs pemetrexed and cisplatin 2. Radiation 3. Participants evaluated for response 4. Lobectomy surgery
Pemetrexed by vein every 21 days for 3 cycles
Carboplatin by vein Every 21 days for 3 cycles
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
48 participants (actual enrollment reported by the registry).
First Submitted
June 13, 2011
First Posted
June 15, 2011
Study Start
May 2011
Date type not reportedThis date has not been verified as actual or estimated.
Radiation treatment 5 days a week for 5-6 weeks.
Pemetrexed by vein every 21 days for 3 cycles
Cisplatin by vein every 21 days for 3 cycles
Radiation treatment 5 days a week for 5-6 weeks.
Surgery
Surgery to remove a portion of the lung where the tumor is located.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
June 2012
Actual (reported)Study Completion
June 2012
Actual (reported)Last Updated
July 26, 2012
Record last verified: 2012-07
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: