Key Insights

Highlights

Success Rate

69% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

23.8%

5 terminated out of 21 trials

Success Rate

68.8%

-17.8% vs benchmark

Late-Stage Pipeline

10%

2 trials in Phase 3/4

Results Transparency

45%

5 of 11 completed with results

Key Signals

5 with results69% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (6)
P 2 (7)
P 3 (2)

Trial Status

Completed11
Terminated5
Unknown3
Not Yet Recruiting1
Active Not Recruiting1

Trial Success Rate

68.8%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT05764928Phase 1Not Yet RecruitingPrimary

Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Pemetrexed + Cisplatin Therapy

NCT05853887Not ApplicableActive Not Recruiting

Liquid Biopsy Based NGS in Newly Diagnosed NSCLC

NCT03177291Phase 1Completed

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

NCT03846310Phase 1Completed

A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer

NCT02831933Phase 2Terminated

Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma

NCT03779191Phase 2Completed

Alectinib in Combination With Bevacizumab in ALK Positive NSCLC

NCT01705184Phase 2Completed

Re-introduction of Pemetrexed and Cisplatin With Prolonged Angiogenic Blocking by Bevacizumab in Advanced Lung Cancer.

NCT04698681Terminated

NGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) Trial

NCT04265534Phase 2Terminated

KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC

NCT03380871Phase 1Completed

A Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung Cancer

NCT02049060Phase 1Completed

Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatin

NCT03912389Phase 3UnknownPrimary

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC

NCT02259582Phase 2CompletedPrimary

A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer

NCT02019979Phase 2Terminated

Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC)

NCT02679443Not ApplicableCompleted

Vitamin Supplementation in NSCLC Patients on Pemetrexed Based Chemotherapy

NCT02852798UnknownPrimary

Apatinib Combined With Docetaxel Monotherapy as Second-line Therapy of Advanced EGFR WT, Non-squamous NSCLC

NCT01161173CompletedPrimary

An Observational Study of Tarceva (Erlotinib) in Routine Daily Clinical Practice as Second Line Treatment in Patients With Non-small Cell Lung Cancer

NCT01473563Phase 2CompletedPrimary

A Study of Home Administration of Pemetrexed as Maintenance Treatment for Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC)

NCT01814163CompletedPrimary

Observational Post-authorization Studies Carboplatin, Paclitaxel and Bevacizumab

NCT01373463Phase 1TerminatedPrimary

Cisplatin and Pemetrexed With Radiation Followed by Lobectomy

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