Success Metrics

Clinical Success Rate
82.9%

Based on 916 completed trials

Completion Rate
83%(916/1105)
Active Trials
259(16%)
Results Posted
43%(393 trials)
Terminated
189(12%)

Phase Distribution

Ph phase_1
393
24%
Ph early_phase_1
25
2%
Ph phase_2
713
44%
Ph phase_3
347
21%
Ph phase_4
4
0%
Ph not_applicable
112
7%

Phase Distribution

418

Early Stage

713

Mid Stage

351

Late Stage

Phase Distribution1594 total trials
Early Phase 1First-in-human
25(1.6%)
Phase 1Safety & dosage
393(24.7%)
Phase 2Efficacy & side effects
713(44.7%)
Phase 3Large-scale testing
347(21.8%)
Phase 4Post-market surveillance
4(0.3%)
N/ANon-phased studies
112(7.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.8%

916 of 1192 finished

Non-Completion Rate

23.2%

276 ended early

Currently Active

259

trials recruiting

Total Trials

1,633

all time

Status Distribution
Active(280)
Completed(916)
Terminated(276)
Other(161)

Detailed Status

Completed916
Terminated189
unknown157
Active, not recruiting138
Recruiting121
Withdrawn87

Development Timeline

Analytics

Development Status

Total Trials
1633
Active
259
Success Rate
82.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 125 (1.6%)
Phase 1393 (24.7%)
Phase 2713 (44.7%)
Phase 3347 (21.8%)
Phase 44 (0.3%)
N/A112 (7.0%)

Trials by Status

unknown15710%
completed91656%
recruiting1217%
suspended40%
enrolling_by_invitation10%
not_yet_recruiting201%
withdrawn875%
active_not_recruiting1388%
terminated18912%

Recent Activity

Clinical Trials (1,633)

Showing 20 of 1,633 trialsScroll for more
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT06992427Phase 3

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT00508443Phase 1

Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)

Active Not Recruiting
NCT06991101Phase 2

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT04929041Phase 2

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Active Not Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT02567435Phase 3

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Active Not Recruiting
NCT05099003Phase 1

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Recruiting
NCT04391049Phase 1

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Active Not Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT04402788Phase 2

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Suspended
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended
NCT07554573Phase 3

Assessment of Biosignature Classification of DCIS for RadioTherapy Benefit Post Lumpectomy (ABCD RT)

Not Yet Recruiting
NCT02344355Phase 2

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Active Not Recruiting
NCT05030298Phase 1

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

Recruiting
NCT07848568Phase 1

Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of Ependymoma

Not Yet Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
1,633