Success Metrics

Clinical Success Rate
83.0%

Based on 908 completed trials

Completion Rate
83%(908/1094)
Active Trials
261(16%)
Results Posted
43%(388 trials)
Terminated
186(11%)

Phase Distribution

Ph phase_1
392
24%
Ph phase_4
4
0%
Ph not_applicable
112
7%
Ph phase_3
345
21%
Ph early_phase_1
25
2%
Ph phase_2
706
43%

Phase Distribution

417

Early Stage

706

Mid Stage

349

Late Stage

Phase Distribution1584 total trials
Early Phase 1First-in-human
25(1.6%)
Phase 1Safety & dosage
392(24.7%)
Phase 2Efficacy & side effects
706(44.6%)
Phase 3Large-scale testing
345(21.8%)
Phase 4Post-market surveillance
4(0.3%)
N/ANon-phased studies
112(7.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.9%

908 of 1181 finished

Non-Completion Rate

23.1%

273 ended early

Currently Active

261

trials recruiting

Total Trials

1,623

all time

Status Distribution
Active(281)
Completed(908)
Terminated(273)
Other(161)

Detailed Status

Completed908
Terminated186
unknown157
Active, not recruiting134
Recruiting127
Withdrawn87

Development Timeline

Analytics

Development Status

Total Trials
1623
Active
261
Success Rate
83.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 125 (1.6%)
Phase 1392 (24.7%)
Phase 2706 (44.6%)
Phase 3345 (21.8%)
Phase 44 (0.3%)
N/A112 (7.1%)

Trials by Status

suspended40%
unknown15710%
withdrawn875%
not_yet_recruiting191%
active_not_recruiting1348%
enrolling_by_invitation10%
recruiting1278%
terminated18611%
completed90856%

Recent Activity

Clinical Trials (1,623)

Showing 20 of 1,623 trialsScroll for more
NCT03104439Phase 2

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Active Not Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT04567771Not Applicable

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Active Not Recruiting
NCT05099003Phase 1

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT06025747Phase 1

A Phase 1 Study of Neoadjuvant Abemaciclib in Combination With Radiation Therapy for Liposarcomas

Recruiting
NCT04402788Phase 2

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT04728230Phase 1

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

Active Not Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT05198830Phase 2

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT02481635Phase 1

A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer

Active Not Recruiting
NCT06295744Not Applicable

Outcomes and Cosmesis With Whole Breast Irradiation and Boost

Recruiting
NCT00085735Phase 3

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Completed
NCT07178301Phase 2

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

Recruiting
NCT00392327Phase 3

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET

Completed
NCT04892173Phase 3

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Recruiting
NCT05110781Phase 2

Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site

Terminated
NCT06859801

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
1,623