Success Metrics

Clinical Success Rate
82.9%

Based on 912 completed trials

Completion Rate
83%(912/1100)
Active Trials
260(16%)
Results Posted
43%(391 trials)
Terminated
188(12%)

Phase Distribution

Ph early_phase_1
25
2%
Ph phase_1
392
24%
Ph phase_2
708
44%
Ph phase_3
346
21%
Ph phase_4
4
0%
Ph not_applicable
112
7%

Phase Distribution

417

Early Stage

708

Mid Stage

350

Late Stage

Phase Distribution1587 total trials
Early Phase 1First-in-human
25(1.6%)
Phase 1Safety & dosage
392(24.7%)
Phase 2Efficacy & side effects
708(44.6%)
Phase 3Large-scale testing
346(21.8%)
Phase 4Post-market surveillance
4(0.3%)
N/ANon-phased studies
112(7.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.8%

912 of 1187 finished

Non-Completion Rate

23.2%

275 ended early

Currently Active

260

trials recruiting

Total Trials

1,626

all time

Status Distribution
Active(278)
Completed(912)
Terminated(275)
Other(161)

Detailed Status

Completed912
Terminated188
unknown157
Active, not recruiting134
Recruiting126
Withdrawn87

Development Timeline

Analytics

Development Status

Total Trials
1626
Active
260
Success Rate
82.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 125 (1.6%)
Phase 1392 (24.7%)
Phase 2708 (44.6%)
Phase 3346 (21.8%)
Phase 44 (0.3%)
N/A112 (7.1%)

Trials by Status

active_not_recruiting1348%
terminated18812%
completed91256%
enrolling_by_invitation10%
recruiting1268%
withdrawn875%
not_yet_recruiting171%
unknown15710%
suspended40%

Recent Activity

Clinical Trials (1,626)

Showing 20 of 1,626 trialsScroll for more
NCT02567435Phase 3

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Active Not Recruiting
NCT02888743Phase 2

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

Active Not Recruiting
NCT04052555Phase 1

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

Active Not Recruiting
NCT07195734Phase 2

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT02954874Phase 3

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Active Not Recruiting
NCT03228537Phase 1

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Active Not Recruiting
NCT05198830Phase 2

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT02567422Phase 1

Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer

Active Not Recruiting
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended
NCT06816927Phase 2

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT04402788Phase 2

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Recruiting
NCT03712605Phase 3

Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial

Active Not Recruiting
NCT07121595Phase 2

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

Recruiting
NCT03775265Phase 3

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Active Not Recruiting
NCT02905591Phase 2

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

Active Not Recruiting
NCT04892173Phase 3

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT04460937Phase 1

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Active Not Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
1,626