Success Metrics

Clinical Success Rate
74.2%

Based on 293 completed trials

Completion Rate
74%(293/395)
Active Trials
193(27%)
Results Posted
83%(242 trials)
Terminated
102(14%)

Phase Distribution

Ph early_phase_1
4
1%
Ph phase_2
337
48%
Ph phase_4
10
1%
Ph not_applicable
11
2%
Ph phase_1
180
25%
Ph phase_3
158
22%

Phase Distribution

184

Early Stage

337

Mid Stage

168

Late Stage

Phase Distribution700 total trials
Early Phase 1First-in-human
4(0.6%)
Phase 1Safety & dosage
180(25.7%)
Phase 2Efficacy & side effects
337(48.1%)
Phase 3Large-scale testing
158(22.6%)
Phase 4Post-market surveillance
10(1.4%)
N/ANon-phased studies
11(1.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.6%

293 of 427 finished

Non-Completion Rate

31.4%

134 ended early

Currently Active

193

trials recruiting

Total Trials

709

all time

Status Distribution
Active(215)
Completed(293)
Terminated(134)
Other(67)

Detailed Status

Completed293
Recruiting109
Terminated102
Active, not recruiting84
unknown65
Withdrawn32

Development Timeline

Analytics

Development Status

Total Trials
709
Active
193
Success Rate
74.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.6%)
Phase 1180 (25.7%)
Phase 2337 (48.1%)
Phase 3158 (22.6%)
Phase 410 (1.4%)
N/A11 (1.6%)

Trials by Status

active_not_recruiting8412%
terminated10214%
completed29341%
unknown659%
not_yet_recruiting213%
enrolling_by_invitation10%
suspended20%
recruiting10915%
withdrawn325%

Recent Activity

Clinical Trials (709)

Showing 20 of 709 trialsScroll for more
NCT06623422Phase 3

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Recruiting
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT05198830Phase 2

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT07739186Phase 2

A Study Evaluating BL-B01D1 in Combination With a PD-1/VEGF Bispecific Antibody Versus Tislelizumab Plus Platinum-doublet Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer(PANKU-Lung06)

Not Yet Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT07739966Phase 1

A Study of DS-3939a in Participants With Solid Tumors

Not Yet Recruiting
NCT05001880Phase 2

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Recruiting
NCT07586202Phase 2

A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

Recruiting
NCT06772623Phase 1

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Recruiting
NCT03793179Phase 3

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Active Not Recruiting
NCT06096844Phase 3

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Recruiting
NCT02194738Not Applicable

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Active Not Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT07492680Phase 2

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Recruiting
NCT04165070Phase 1

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Recruiting
NCT06745882Phase 2

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

Recruiting
NCT04988295Phase 3

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Active Not Recruiting
NCT05258279Phase 2

Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations

Completed
NCT04736173Phase 2

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Active Not Recruiting
NCT03425643Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
709