Success Metrics

Clinical Success Rate
79.4%

Based on 1,052 completed trials

Completion Rate
79%(1052/1325)
Active Trials
587(26%)
Results Posted
66%(697 trials)
Terminated
273(12%)

Phase Distribution

Ph phase_3
475
21%
Ph phase_1
601
26%
Ph phase_2
1,131
49%
Ph phase_4
18
1%
Ph not_applicable
33
1%
Ph early_phase_1
14
1%

Phase Distribution

615

Early Stage

1131

Mid Stage

493

Late Stage

Phase Distribution2272 total trials
Early Phase 1First-in-human
14(0.6%)
Phase 1Safety & dosage
601(26.5%)
Phase 2Efficacy & side effects
1,131(49.8%)
Phase 3Large-scale testing
475(20.9%)
Phase 4Post-market surveillance
18(0.8%)
N/ANon-phased studies
33(1.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.7%

1052 of 1408 finished

Non-Completion Rate

25.3%

356 ended early

Currently Active

587

trials recruiting

Total Trials

2,295

all time

Status Distribution
Active(651)
Completed(1052)
Terminated(356)
Other(236)

Detailed Status

Completed1052
Recruiting326
Terminated273
Active, not recruiting261
unknown233
Withdrawn83

Development Timeline

Analytics

Development Status

Total Trials
2295
Active
587
Success Rate
79.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 114 (0.6%)
Phase 1601 (26.5%)
Phase 21131 (49.8%)
Phase 3475 (20.9%)
Phase 418 (0.8%)
N/A33 (1.5%)

Trials by Status

active_not_recruiting26111%
suspended30%
terminated27312%
completed105246%
enrolling_by_invitation10%
unknown23310%
withdrawn834%
not_yet_recruiting633%
recruiting32614%

Recent Activity

Clinical Trials (2,295)

Showing 20 of 2,295 trialsScroll for more
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Recruiting
NCT06439225Phase 3

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes

Recruiting
NCT04671667Phase 2

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recruiting
NCT07100080Phase 2

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Recruiting
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT07005128Phase 3

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT05925491Phase 2

Pembrolizumab in Locally Advanced Sinonasal Carcinoma

Recruiting
NCT05001880Phase 2

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Recruiting
NCT03967977Phase 3

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT05635708Phase 2

A Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung Cancer

Active Not Recruiting
NCT06946797Phase 2

A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06712316Phase 2

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT06741644Phase 1

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Recruiting
NCT07005102Phase 2

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,295