Success Metrics

Clinical Success Rate
78.9%

Based on 1,072 completed trials

Completion Rate
79%(1072/1358)
Active Trials
588(25%)
Results Posted
67%(718 trials)
Terminated
286(12%)

Phase Distribution

Ph phase_1
611
26%
Ph phase_3
481
21%
Ph phase_2
1,146
49%
Ph phase_4
19
1%
Ph early_phase_1
14
1%
Ph not_applicable
33
1%

Phase Distribution

625

Early Stage

1146

Mid Stage

500

Late Stage

Phase Distribution2304 total trials
Early Phase 1First-in-human
14(0.6%)
Phase 1Safety & dosage
611(26.5%)
Phase 2Efficacy & side effects
1,146(49.7%)
Phase 3Large-scale testing
481(20.9%)
Phase 4Post-market surveillance
19(0.8%)
N/ANon-phased studies
33(1.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.3%

1072 of 1442 finished

Non-Completion Rate

25.7%

370 ended early

Currently Active

588

trials recruiting

Total Trials

2,328

all time

Status Distribution
Active(657)
Completed(1072)
Terminated(370)
Other(229)

Detailed Status

Completed1072
Recruiting324
Terminated286
Active, not recruiting264
unknown226
Withdrawn84

Development Timeline

Analytics

Development Status

Total Trials
2328
Active
588
Success Rate
78.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 114 (0.6%)
Phase 1611 (26.5%)
Phase 21146 (49.7%)
Phase 3481 (20.9%)
Phase 419 (0.8%)
N/A33 (1.4%)

Trials by Status

completed107246%
active_not_recruiting26411%
not_yet_recruiting673%
unknown22610%
terminated28612%
withdrawn844%
enrolling_by_invitation20%
recruiting32414%
suspended30%

Recent Activity

Clinical Trials (2,328)

Showing 20 of 2,328 trialsScroll for more
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT02227199Phase 1

Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Completed
NCT06096844Phase 3

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Recruiting
NCT03858322Phase 1

'ADVANCE' (A Pilot Trial)

Active Not Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT04166409Phase 3

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Recruiting
NCT02515877Phase 1

Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers

Completed
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT04924101Phase 2

Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)

Completed
NCT05198830Phase 2

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT06416410Phase 3

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation

Recruiting
NCT06692738Phase 3

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Recruiting
NCT03871257Phase 3

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Active Not Recruiting
NCT05489211Phase 2

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Recruiting
NCT05001880Phase 2

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Recruiting
NCT06712316Phase 2

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Recruiting
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,328