Success Metrics

Clinical Success Rate
81.0%

Based on 1,127 completed trials

Completion Rate
81%(1127/1392)
Active Trials
487(21%)
Results Posted
54%(613 trials)
Terminated
265(11%)

Phase Distribution

Ph early_phase_1
13
1%
Ph phase_1
527
22%
Ph not_applicable
62
3%
Ph phase_3
568
24%
Ph phase_2
1,163
49%
Ph phase_4
17
1%

Phase Distribution

540

Early Stage

1163

Mid Stage

585

Late Stage

Phase Distribution2350 total trials
Early Phase 1First-in-human
13(0.6%)
Phase 1Safety & dosage
527(22.4%)
Phase 2Efficacy & side effects
1,163(49.5%)
Phase 3Large-scale testing
568(24.2%)
Phase 4Post-market surveillance
17(0.7%)
N/ANon-phased studies
62(2.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.3%

1127 of 1496 finished

Non-Completion Rate

24.7%

369 ended early

Currently Active

487

trials recruiting

Total Trials

2,370

all time

Status Distribution
Active(575)
Completed(1127)
Terminated(369)
Other(299)

Detailed Status

Completed1127
unknown290
Recruiting280
Terminated265
Active, not recruiting207
Withdrawn104

Development Timeline

Analytics

Development Status

Total Trials
2370
Active
487
Success Rate
81.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 113 (0.6%)
Phase 1527 (22.4%)
Phase 21163 (49.5%)
Phase 3568 (24.2%)
Phase 417 (0.7%)
N/A62 (2.6%)

Trials by Status

active_not_recruiting2079%
completed112748%
suspended90%
withdrawn1044%
recruiting28012%
not_yet_recruiting813%
terminated26511%
enrolling_by_invitation70%
unknown29012%

Recent Activity

Clinical Trials (2,370)

Showing 20 of 2,370 trialsScroll for more
NCT02999087Phase 3

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

Active Not Recruiting
NCT03576417Phase 3

A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck

Active Not Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT04991025Phase 2

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

Recruiting
NCT02595424Phase 2

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Active Not Recruiting
NCT07680764Phase 2

A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT06623422Phase 3

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Recruiting
NCT03340896Phase 3

Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT

Active Not Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Suspended
NCT07856069Phase 2

Arsenic Trioxide Combined With Chemotherapy for Relapsed SHH-Activated and/or TP53-Mutant Medulloblastoma

Not Yet Recruiting
NCT07853690Not Applicable

Histotripsy in Biliary Tract Cancer

Not Yet Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Suspended
NCT02445391Phase 3

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Active Not Recruiting
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting
NCT06996782Phase 1

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,370