Success Metrics

Clinical Success Rate
81.3%

Based on 1,102 completed trials

Completion Rate
81%(1102/1356)
Active Trials
478(21%)
Results Posted
54%(598 trials)
Terminated
254(11%)

Phase Distribution

Ph phase_1
523
23%
Ph phase_2
1,122
49%
Ph not_applicable
61
3%
Ph phase_3
556
24%
Ph early_phase_1
12
1%
Ph phase_4
15
1%

Phase Distribution

535

Early Stage

1122

Mid Stage

571

Late Stage

Phase Distribution2289 total trials
Early Phase 1First-in-human
12(0.5%)
Phase 1Safety & dosage
523(22.8%)
Phase 2Efficacy & side effects
1,122(49.0%)
Phase 3Large-scale testing
556(24.3%)
Phase 4Post-market surveillance
15(0.7%)
N/ANon-phased studies
61(2.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.7%

1102 of 1456 finished

Non-Completion Rate

24.3%

354 ended early

Currently Active

478

trials recruiting

Total Trials

2,307

all time

Status Distribution
Active(547)
Completed(1102)
Terminated(354)
Other(304)

Detailed Status

Completed1102
unknown299
Recruiting279
Terminated254
Active, not recruiting199
Withdrawn100

Development Timeline

Analytics

Development Status

Total Trials
2307
Active
478
Success Rate
81.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (0.5%)
Phase 1523 (22.8%)
Phase 21122 (49.0%)
Phase 3556 (24.3%)
Phase 415 (0.7%)
N/A61 (2.7%)

Trials by Status

completed110248%
suspended50%
enrolling_by_invitation50%
not_yet_recruiting643%
unknown29913%
withdrawn1004%
active_not_recruiting1999%
recruiting27912%
terminated25411%

Recent Activity

Clinical Trials (2,307)

Showing 20 of 2,307 trialsScroll for more
NCT05659381Phase 3

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

Recruiting
NCT07100080Phase 2

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Recruiting
NCT05498220Phase 2

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Terminated
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT01857934Phase 2

Therapy for Children With Advanced Stage Neuroblastoma

Completed
NCT05967182Phase 2

A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma

Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT06702033Phase 2

The Minimalist Trial-2

Recruiting
NCT02128906Phase 2

Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Recruiting
NCT05925491Phase 2

Pembrolizumab in Locally Advanced Sinonasal Carcinoma

Recruiting
NCT04671667Phase 2

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recruiting
NCT06467357Phase 3

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Recruiting
NCT07043400Phase 3

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT06946797Phase 2

A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT04924062Phase 3

Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966)-China Extension Study

Completed
NCT03661320Phase 3

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

Active Not Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT04580771Phase 2

A Vaccine (PDS0101) and Chemoradiation for the Treatment of Stage IB3-IVA Cervical Cancer, the IMMUNOCERV Trial

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,307