Success Metrics

Clinical Success Rate
81.2%

Based on 1,115 completed trials

Completion Rate
81%(1115/1373)
Active Trials
475(20%)
Results Posted
54%(603 trials)
Terminated
258(11%)

Phase Distribution

Ph phase_1
527
23%
Ph phase_4
16
1%
Ph not_applicable
61
3%
Ph phase_2
1,133
49%
Ph phase_3
558
24%
Ph early_phase_1
12
1%

Phase Distribution

539

Early Stage

1133

Mid Stage

574

Late Stage

Phase Distribution2307 total trials
Early Phase 1First-in-human
12(0.5%)
Phase 1Safety & dosage
527(22.8%)
Phase 2Efficacy & side effects
1,133(49.1%)
Phase 3Large-scale testing
558(24.2%)
Phase 4Post-market surveillance
16(0.7%)
N/ANon-phased studies
61(2.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

1115 of 1476 finished

Non-Completion Rate

24.5%

361 ended early

Currently Active

475

trials recruiting

Total Trials

2,326

all time

Status Distribution
Active(550)
Completed(1115)
Terminated(361)
Other(300)

Detailed Status

Completed1115
unknown294
Recruiting274
Terminated258
Active, not recruiting201
Withdrawn103

Development Timeline

Analytics

Development Status

Total Trials
2326
Active
475
Success Rate
81.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (0.5%)
Phase 1527 (22.8%)
Phase 21133 (49.1%)
Phase 3558 (24.2%)
Phase 416 (0.7%)
N/A61 (2.6%)

Trials by Status

enrolling_by_invitation70%
completed111548%
recruiting27412%
not_yet_recruiting683%
withdrawn1034%
unknown29413%
suspended60%
terminated25811%
active_not_recruiting2019%

Recent Activity

Clinical Trials (2,326)

Showing 20 of 2,326 trialsScroll for more
NCT07486817Phase 2

Beamion 44: A Study to Test How Well Zongertinib is Tolerated by People With Advanced Non-small Cell Lung Cancer With HER2 Mutations When Given in Combination With Chemotherapy With or Without Pembrolizumab

Recruiting
NCT07646301Phase 2

Iparomlimab and Tuvonralimab Plus Paclitaxel and Platinum as Neoadjuvant Therapy for Locally Advanced Cervical Cancer

Recruiting
NCT07216703Phase 3

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Recruiting
NCT05058651Phase 2

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Recruiting
NCT06657144Phase 1

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07321912Phase 2

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Recruiting
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT01810913Phase 2

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT01154920Phase 2

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT06772623Phase 1

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT07190248Phase 3

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Recruiting
NCT06467357Phase 3

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,326