Success Metrics

Clinical Success Rate
81.2%

Based on 1,124 completed trials

Completion Rate
81%(1124/1385)
Active Trials
473(20%)
Results Posted
54%(608 trials)
Terminated
261(11%)

Phase Distribution

Ph phase_1
526
22%
Ph early_phase_1
12
1%
Ph not_applicable
61
3%
Ph phase_3
561
24%
Ph phase_4
16
1%
Ph phase_2
1,143
49%

Phase Distribution

538

Early Stage

1143

Mid Stage

577

Late Stage

Phase Distribution2319 total trials
Early Phase 1First-in-human
12(0.5%)
Phase 1Safety & dosage
526(22.7%)
Phase 2Efficacy & side effects
1,143(49.3%)
Phase 3Large-scale testing
561(24.2%)
Phase 4Post-market surveillance
16(0.7%)
N/ANon-phased studies
61(2.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

1124 of 1489 finished

Non-Completion Rate

24.5%

365 ended early

Currently Active

473

trials recruiting

Total Trials

2,338

all time

Status Distribution
Active(549)
Completed(1124)
Terminated(365)
Other(300)

Detailed Status

Completed1124
unknown292
Recruiting274
Terminated261
Active, not recruiting199
Withdrawn104

Development Timeline

Analytics

Development Status

Total Trials
2338
Active
473
Success Rate
81.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (0.5%)
Phase 1526 (22.7%)
Phase 21143 (49.3%)
Phase 3561 (24.2%)
Phase 416 (0.7%)
N/A61 (2.6%)

Trials by Status

unknown29212%
completed112448%
withdrawn1044%
active_not_recruiting1999%
enrolling_by_invitation70%
not_yet_recruiting693%
recruiting27412%
suspended80%
terminated26111%

Recent Activity

Clinical Trials (2,338)

Showing 20 of 2,338 trialsScroll for more
NCT01810913Phase 2

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Suspended
NCT06331468Phase 2

Hypofractionated Radiochemotherapy

Recruiting
NCT07195734Phase 2

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT02194738Not Applicable

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Active Not Recruiting
NCT03811015Phase 3

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Active Not Recruiting
NCT06457503Phase 4

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT06745882Phase 2

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

Recruiting
NCT05198830Phase 2

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT04671667Phase 2

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recruiting
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT06050252Phase 2

Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

Recruiting
NCT02486718Phase 3

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Active Not Recruiting
NCT04974944Phase 2

First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in Advanced Cervical Cancer

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
2,338