Computer-Based Training for Cognitive Enhancement: In Home Study
1 other identifier
interventional
182
1 country
1
Brief Summary
The primary objective of this study is to evaluate the effects of a computer-based training program on the memory and cognitive abilities of mature individuals undergoing healthy aging.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2005
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2006
CompletedFirst Submitted
Initial submission to the registry
June 15, 2006
CompletedFirst Posted
Study publicly available on registry
June 20, 2006
CompletedNovember 2, 2015
October 1, 2015
10 months
June 15, 2006
October 29, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Evaluation of training effects.
Secondary Outcomes (1)
Safety effects of computer-based training.
Study Arms (3)
Experimental Treatment
EXPERIMENTALComputerized Plasticity-Based Adaptive Cognitive Training
Active Control
ACTIVE COMPARATOREducational DVDs
No Contact Control
NO INTERVENTIONInterventions
Eligibility Criteria
You may qualify if:
- A)Participants must be at least 60 years old B)Participants must have a Mini-Mental State Exam (MMSE) score of 24 or higher to ensure that participants do not meet common criteria for dementia C)Participants must be a native English speaker D)Participants must be able to see well enough to read the consent form E)Participants must be able to hear well enough to understand ordinary spoken conversation in a slightly noisy room F)Participants must be willing to commit to the time requirements of the study and not have any scheduled trips or absences for more than 1 week during the training.
You may not qualify if:
- B)Participants must not have had a head trauma that caused them to lose consciousness.
- C)Participants must not have had a stroke within the past year; or have had a stroke that has left them with expressive or receptive language problems.
- D)Participants must not have any central nervous system disorder that could contribute to cognitive impairment.
- E)Participants must not have a tremor preventing the use of a computer mouse or other pointing device.
- F)Participants must not currently be active in another clinical trial.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Posit Science Corporation
San Francisco, California, 94108, United States
Related Publications (1)
Mahncke HW, Connor BB, Appelman J, Ahsanuddin ON, Hardy JL, Wood RA, Joyce NM, Boniske T, Atkins SM, Merzenich MM. Memory enhancement in healthy older adults using a brain plasticity-based training program: a randomized, controlled study. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12523-8. doi: 10.1073/pnas.0605194103. Epub 2006 Aug 3.
PMID: 16888038RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Henry W Mahncke, PhD
Posit Science Corporation
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 15, 2006
First Posted
June 20, 2006
Study Start
March 1, 2005
Primary Completion
January 1, 2006
Study Completion
January 1, 2006
Last Updated
November 2, 2015
Record last verified: 2015-10