Activities for Cognitive Enhancement of Seniors
ACE-Seniors
Tai Chi and Guided Autobiography for Remediation of Age-related Cognitive Decline
2 other identifiers
interventional
175
1 country
1
Brief Summary
Cognitive aging and cognitive decline are important public health concerns in an aging US population. The investigators will conduct a randomized controlled trail among healthy older adults to assess effects of several innovative activities on remediation of age-related cognitive decline.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2010
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2010
CompletedFirst Submitted
Initial submission to the registry
March 25, 2010
CompletedFirst Posted
Study publicly available on registry
March 29, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedNovember 20, 2014
November 1, 2014
2.3 years
March 25, 2010
November 18, 2014
Conditions
Outcome Measures
Primary Outcomes (1)
Cognitive (executive function and episodic memory)
6 and 12 months
Secondary Outcomes (3)
Other cognitive measures
6 and 12 months
Physical performance and other non-cognitive measures
6 and 12 months
Adherence and retention
6 and 12 months
Study Arms (6)
Tai Chi
EXPERIMENTALTai Chi exercises
Guided autobiography
EXPERIMENTALAutobiographical writing during class sessions and at home
Qigong
EXPERIMENTALQigong exercises (exploratory, not part of the original protocol, added to gain experience with this intervention)
Successful aging
ACTIVE COMPARATORSeminars on the theme of successful aging
Combination
EXPERIMENTALCombination of Tai Chi exercises and autobiographical writing
Comparison
PLACEBO COMPARATORNo assigned experimental activity (exploratory, not part of the original protocol, added to gain experience with a placebo comparator)
Interventions
Eligibility Criteria
You may qualify if:
- years of age or older.
- No other household member already enrolled.
- In reasonably good health: no serious cognitive problem; free of any condition that would limit your ability to participate in Tai Chi classes (a moderate intensity exercise), in Qigong exercises, in a writing program, or in a seminar series.
- Not presently engaged in a regular exercise program; not presently engaged in Tai Chi Qigong or another form of Eastern exercise; and not a regular writer.
- Not now engaged in research to enhance cognitive skills.
- Willing to travel to Stanford for ACE-Seniors program classes. Planning to be in the area during most of the coming year;
- Willing to be assigned randomly (by chance) to one of the ACE-Senior activities.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Stanford Universitylead
- National Institute on Aging (NIA)collaborator
Study Sites (1)
Stanford University School of Medicine
Stanford, California, 94305, United States
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Dr Victor Henderson
Stanford University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
March 25, 2010
First Posted
March 29, 2010
Study Start
March 1, 2010
Primary Completion
July 1, 2012
Study Completion
December 1, 2013
Last Updated
November 20, 2014
Record last verified: 2014-11