Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI
Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and Mild Cognitive Impairment
1 other identifier
interventional
40
1 country
1
Brief Summary
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in an aging population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 13, 2024
CompletedFirst Posted
Study publicly available on registry
February 21, 2024
CompletedStudy Start
First participant enrolled
June 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
March 30, 2026
CompletedMay 16, 2025
May 1, 2025
10 months
February 13, 2024
May 13, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Verbal Leaning task
Change in total score from Open-Trial Selective Reminding Test (OT-SRT)
Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]
Participation in Everyday life
Change in total score from Participation Assessment with Recombined Tools
Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]
Secondary Outcomes (1)
Functional Neuroimaging
Two points in time: pre-treatment, immediately following treatment
Study Arms (2)
Experimental group
EXPERIMENTALThe experimental group will receive memory techniques training administered twice a week for four weeks (8 training sessions).
Control group
PLACEBO COMPARATORThe control group will receive memory exercises administered twice a week for four weeks (8 sessions).
Interventions
Eligibility Criteria
You may qualify if:
- read and speak English fluently
You may not qualify if:
- prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke).
- history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis).
- significant alcohol or drug abuse history (inpatient treatment).
- Benzodiazepines and steroid use
- Diagnosis of dementia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Kessler Foundation
East Hanover, New Jersey, 07936, United States
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director
Study Record Dates
First Submitted
February 13, 2024
First Posted
February 21, 2024
Study Start
June 1, 2025
Primary Completion
March 30, 2026
Study Completion
March 30, 2026
Last Updated
May 16, 2025
Record last verified: 2025-05