NCT00006192

Brief Summary

To document cardiovascular disease and cardiovascular disease risk factors among 1,200 Native Alaskans who are members of approximately 40 families.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Aug 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2000

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 31, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 1, 2000

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2005

Completed
Last Updated

July 29, 2016

Status Verified

May 1, 2009

Enrollment Period

5.3 years

First QC Date

August 31, 2000

Last Update Submit

July 28, 2016

Conditions

Heart DiseasesCardiovascular DiseasesAtherosclerosisHypertensionDiabetes MellitusCoronary Arteriosclerosis

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (4)

  • Nobmann ED, Ponce R, Mattil C, Devereux R, Dyke B, Ebbesson SO, Laston S, MacCluer J, Robbins D, Romenesko T, Ruotolo G, Wenger CR, Howard BV; GOCADAN study, 2000-2003. Dietary intakes vary with age among Eskimo adults of Northwest Alaska in the GOCADAN study, 2000-2003. J Nutr. 2005 Apr;135(4):856-62. doi: 10.1093/jn/135.4.856.

    PMID: 15795447BACKGROUND

  • Howard BV, Devereux RB, Cole SA, Davidson M, Dyke B, Ebbesson SO, Epstein SE, Robinson DR, Jarvis B, Kaufman DJ, Laston S, MacCluer JW, Okin PM, Roman MJ, Romenesko T, Ruotolo G, Swenson M, Wenger CR, Williams-Blangero S, Zhu J, Saccheus C, Fabsitz RR, Robbins DC. A genetic and epidemiologic study of cardiovascular disease in Alaska natives (GOCADAN): design and methods. Int J Circumpolar Health. 2005 Jun;64(3):206-21. doi: 10.3402/ijch.v64i3.17985.

    PMID: 16050315BACKGROUND

  • Carter EA, MacCluer JW, Dyke B, Howard BV, Devereux RB, Ebbesson SO, Resnick HE. Diabetes mellitus and impaired fasting glucose in Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. Diabetologia. 2006 Jan;49(1):29-35. doi: 10.1007/s00125-005-0071-9. Epub 2005 Dec 21.

    PMID: 16369773BACKGROUND

  • Voruganti VS, Cole SA, Ebbesson SO, Goring HH, Haack K, Laston S, Wenger CR, Tejero ME, Devereux RB, Fabsitz RR, MacCluer JW, Umans JG, Howard BV, Comuzzie AG. Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos. Am J Clin Nutr. 2010 Jun;91(6):1574-83. doi: 10.3945/ajcn.2009.28927. Epub 2010 Apr 21.

    PMID: 20410100DERIVED

MeSH Terms

Conditions

Heart DiseasesCardiovascular DiseasesAtherosclerosisHypertensionDiabetes MellitusCoronary Artery Disease

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesCoronary DiseaseMyocardial Ischemia

Study Officials

  • Giacomo Ruotolo

    Medstar Health Research Institute

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

August 31, 2000

First Posted

September 1, 2000

Study Start

August 1, 2000

Primary Completion

December 1, 2005

Study Completion

December 1, 2005

Last Updated

July 29, 2016

Record last verified: 2009-05