NCT00006297

Brief Summary

To investigate whether traditional risk factors and novel risk factors predict higher risk of atherosclerotic cardiovascular disease (ASCVD) in a prospective study of incident dialysis patients.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2000

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

September 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 26, 2000

Completed
4.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2005

Completed
Last Updated

February 18, 2016

Status Verified

October 1, 2005

First QC Date

September 25, 2000

Last Update Submit

February 17, 2016

Conditions

Eligibility Criteria

AgeUp to 100 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (14)

  • Miskulin DC, Meyer KB, Martin AA, Fink NE, Coresh J, Powe NR, Klag MJ, Levey AS; Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) Study. Comorbidity and its change predict survival in incident dialysis patients. Am J Kidney Dis. 2003 Jan;41(1):149-61. doi: 10.1053/ajkd.2003.50034.

    PMID: 12500232BACKGROUND
  • Astor BC, Eustace JA, Klag MJ, Powe NR, Longenecker JC, Fink NE, Marcovina SM, Coresh J; CHOICE Study. Race-specific association of lipoprotein(a) with vascular access interventions in hemodialysis patients: the CHOICE Study. Kidney Int. 2002 Mar;61(3):1115-23. doi: 10.1046/j.1523-1755.2002.00194.x.

    PMID: 11849466BACKGROUND
  • Astor BC, Eustace JA, Powe NR, Klag MJ, Sadler JH, Fink NE, Coresh J. Timing of nephrologist referral and arteriovenous access use: the CHOICE Study. Am J Kidney Dis. 2001 Sep;38(3):494-501. doi: 10.1053/ajkd.2001.26833.

    PMID: 11532680BACKGROUND
  • Liu Y, Coresh J, Eustace JA, Longenecker JC, Jaar B, Fink NE, Tracy RP, Powe NR, Klag MJ. Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition. JAMA. 2004 Jan 28;291(4):451-9. doi: 10.1001/jama.291.4.451.

    PMID: 14747502BACKGROUND
  • Plantinga LC, Fink NE, Sadler JH, Levey AS, Levin NW, Rubin HR, Coresh J, Klag MJ, Powe NR. Frequency of patient-physician contact and patient outcomes in hemodialysis care. J Am Soc Nephrol. 2004 Jan;15(1):210-8. doi: 10.1097/01.asn.0000106101.48237.9d.

    PMID: 14694175BACKGROUND
  • Longenecker JC, Coresh J, Marcovina SM, Powe NR, Levey AS, Giaculli F, Fink NE, Klag MJ. Lipoprotein(a) and prevalent cardiovascular disease in a dialysis population: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) study. Am J Kidney Dis. 2003 Jul;42(1):108-16. doi: 10.1016/s0272-6386(03)00413-x.

    PMID: 12830462BACKGROUND
  • Fox CS, Longenecker JC, Powe NR, Klag MJ, Fink NE, Parekh R, Coresh J; CHOICE Study. Undertreatment of hyperlipidemia in a cohort of United States kidney dialysis patients. Clin Nephrol. 2004 May;61(5):299-307. doi: 10.5414/cnp61299.

    PMID: 15182124BACKGROUND
  • Unruh ML, Levey AS, D'Ambrosio C, Fink NE, Powe NR, Meyer KB; Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) Study. Restless legs symptoms among incident dialysis patients: association with lower quality of life and shorter survival. Am J Kidney Dis. 2004 May;43(5):900-9. doi: 10.1053/j.ajkd.2004.01.013.

    PMID: 15112181BACKGROUND
  • Plantinga LC, Fink NE, Jaar BG, Sadler JH, Coresh J, Klag MJ, Levey AS, Powe NR. Frequency of sit-down patient care rounds, attainment of clinical performance targets, hospitalization, and mortality in hemodialysis patients. J Am Soc Nephrol. 2004 Dec;15(12):3144-53. doi: 10.1097/01.ASN.0000146424.91128.2A.

    PMID: 15579518BACKGROUND
  • Jaar BG, Coresh J, Plantinga LC, Fink NE, Klag MJ, Levey AS, Levin NW, Sadler JH, Kliger A, Powe NR. Comparing the risk for death with peritoneal dialysis and hemodialysis in a national cohort of patients with chronic kidney disease. Ann Intern Med. 2005 Aug 2;143(3):174-83. doi: 10.7326/0003-4819-143-3-200508020-00003.

    PMID: 16061915BACKGROUND
  • Liu Y, Berthier-Schaad Y, Fink NE, Fallin MD, Tracy RP, Klag MJ, Smith MW, Coresh J. Beta-fibrinogen haplotypes and the risk for cardiovascular disease in a dialysis cohort. Am J Kidney Dis. 2005 Jul;46(1):78-85. doi: 10.1053/j.ajkd.2005.03.008.

    PMID: 15983960BACKGROUND
  • Longenecker JC, Klag MJ, Marcovina SM, Liu YM, Jaar BG, Powe NR, Fink NE, Levey AS, Coresh J. High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients. J Am Soc Nephrol. 2005 Jun;16(6):1794-802. doi: 10.1681/ASN.2004110922. Epub 2005 Mar 30.

    PMID: 15800123BACKGROUND
  • Astor BC, Eustace JA, Powe NR, Klag MJ, Fink NE, Coresh J; CHOICE Study. Type of vascular access and survival among incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study. J Am Soc Nephrol. 2005 May;16(5):1449-55. doi: 10.1681/ASN.2004090748. Epub 2005 Mar 23.

    PMID: 15788468BACKGROUND
  • Plantinga LC, Jaar BG, Fink NE, Sadler JH, Levin NW, Coresh J, Klag MJ, Powe NR. Frequency of patient-physician contact in chronic kidney disease care and achievement of clinical performance targets. Int J Qual Health Care. 2005 Apr;17(2):115-21. doi: 10.1093/intqhc/mzi010. Epub 2005 Feb 21.

    PMID: 15723821BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesAtherosclerosisKidney Failure, Chronic

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesRenal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Josef Coresh

    Johns Hopkins University

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

September 25, 2000

First Posted

September 26, 2000

Study Start

September 1, 2000

Study Completion

July 1, 2005

Last Updated

February 18, 2016

Record last verified: 2005-10