NCT00005745

Brief Summary

To quantify the association between multiple intentional weight losses (i.e., weight fluctuations) and the development of hypertension and diabetes mellitus among 50,790 female nurses participating in the ongoing Nurses' Health Study II. In addition to assessing the consequences of weight fluctuations, their correlates and course were identified.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jan 1998

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1998

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
2.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2002

Completed
Last Updated

March 16, 2016

Status Verified

September 1, 2004

First QC Date

May 25, 2000

Last Update Submit

March 15, 2016

Conditions

Eligibility Criteria

AgeUp to 100 Years
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

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Sponsors & Collaborators

Related Publications (1)

  • Field AE, Wing RR, Manson JE, Spiegelman DL, Willett WC. Relationship of a large weight loss to long-term weight change among young and middle-aged US women. Int J Obes Relat Metab Disord. 2001 Aug;25(8):1113-21. doi: 10.1038/sj.ijo.0801643.

    PMID: 11477495BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesDiabetes MellitusHeart DiseasesHypertension

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesVascular Diseases

Study Officials

  • Alison Field

    Brigham and Women's Hospital

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

January 1, 1998

Study Completion

December 1, 2002

Last Updated

March 16, 2016

Record last verified: 2004-09