NCT00021918

Brief Summary

To examine the independent association of serum total homocysteine and C-reactive protein with arteriosclerotic cardiovascular disease morbidity and mortality.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 2001

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2001

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 10, 2001

Completed
Same day until next milestone

First Posted

Study publicly available on registry

August 10, 2001

Completed
2.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2004

Completed
Last Updated

February 18, 2016

Status Verified

October 1, 2005

First QC Date

August 10, 2001

Last Update Submit

February 17, 2016

Conditions

Cardiovascular DiseasesAtherosclerosisHeart DiseasesDiabetes Mellitus, Non-insulin DependentHypertensionDiabetes Mellitus

Eligibility Criteria

Age30 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (3)

  • Friedman AN, Hunsicker LG, Selhub J, Bostom AG. Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy. Atherosclerosis. 2004 Jan;172(1):121-5. doi: 10.1016/j.atherosclerosis.2003.09.011.

    PMID: 14709365BACKGROUND

  • Friedman AN, Hunsicker LG, Selhub J, Bostom AG; Collaborative Study Group. Total plasma homocysteine and arteriosclerotic outcomes in type 2 diabetes with nephropathy. J Am Soc Nephrol. 2005 Nov;16(11):3397-402. doi: 10.1681/ASN.2004100846. Epub 2005 Sep 14.

    PMID: 16162814BACKGROUND

  • Friedman AN, Hunsicker LG, Selhub J, Bostom AG; Collaborative Study Group. C-reactive protein as a predictor of total arteriosclerotic outcomes in type 2 diabetic nephropathy. Kidney Int. 2005 Aug;68(2):773-8. doi: 10.1111/j.1523-1755.2005.00456.x.

    PMID: 16014055BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesAtherosclerosisHeart DiseasesDiabetes Mellitus, Type 2HypertensionDiabetes Mellitus

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Andrew Bostom

    Memorial hospital

Study Design

Study Type
observational
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

August 10, 2001

First Posted

August 10, 2001

Study Start

April 1, 2001

Study Completion

June 1, 2004

Last Updated

February 18, 2016

Record last verified: 2005-10