NCT00005192

Brief Summary

To determine why Black Americans have a higher prevalence of hypertension than whites by examining the interactions of psychosocial stressors and suppressed hostility with genetic or constitutional factors.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jul 1986

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 1986

Completed
13.9 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
Last Updated

January 15, 2016

Status Verified

January 1, 2016

Enrollment Period

19.9 years

First QC Date

May 25, 2000

Last Update Submit

January 14, 2016

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Eligibility Criteria

Age25 Years - 54 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (44)

  • Gellman MD, Ironson GH, Spitzer SB, Keenan M, Schneiderman N, Weidler DJ: Ambulatory Blood Pressure as a Function of Race, Gender, Place, and Mood. Circulation, 74(Suppl.)2, 319, 1986

    BACKGROUND

  • Spitzer SB, Carver CS, Gerace TA, Tischenkel N, Gellman M, Schneiderman N: Locus of Control, John Henryism, Monitoring-Blunting, and Reactivity in the Miami Minority Hypertension Project. Society of Behavioral Medicine, 1986

    BACKGROUND

  • Tischenkel N, Schneiderman N, Nelesen R, Vorp R, Gellman M, Gerace T, McCabe PM: Cardiovascular and Neurohumoral Baselines and Reactivity in the Miami Minority Hypertension Project. Society of Behavioral Medicine, 1986

    BACKGROUND

  • Weintraub JK, Carver CS, McCabe PM, Spitzer S, Schneiderman J: Anger, Hostility, and Reactivity in the Miami Minority Hypertension Project. Society of Behavioral Medicine, 1986

    BACKGROUND

  • Tishenkel N, Gellman M, Nelesen R, Schneiderman N: Behavioral Factors Affecting Blood Pressure in Blacks. Cardiovascular Disease Epidemiology Newsletter, 315, 1986

    BACKGROUND

  • Larsen P, Schneiderman N, Pasin RD: Physiological Bases of Cardiovascular Psychophysiology. In: Coles M, Donchin E, Porges S (Eds), Psychophysiology: Systems, Processes and Applications. Guilford, 1986

    BACKGROUND

  • Kaufman MP, Schneiderman N: Physiological Bases of Respiratory Psychophysiology. In: Coles M, Donchin E, Porges S (Eds), Psychophysiology: Systems, Processes and Applications. Guilford, 1986

    BACKGROUND

  • Dimsdale J, Alpert B, Schneiderman N: Exercise as a Modulator of Cardiovascular Reactivity. In: Matthews K et al (Ed), Handbook of Stress, Reactivity, and Cardiovascular Disease. Wiley, 1986

    BACKGROUND

  • Schneiderman N, Pickering T: Cardiovascular Measures of Physiologic Reactivity. In: Matthews K et al (Ed), Handbook of Stress, Reactivity, and Cardiovascular Disease. Wiley, 1986

    BACKGROUND

  • Schneiderman N, Tischenkel N, Nelesen R: Anger, Aerobics, and Autonomic Reactivity. In: Schmidt T, Dembroski T, Blumchen C (Eds), Biological and Psychological Factors in Cardiovascular Disease. Springer, 1986

    BACKGROUND

  • Schneiderman N. Psychophysiologic factors in atherogenesis and coronary artery disease. Circulation. 1987 Jul;76(1 Pt 2):I41-7.

    PMID: 3297408BACKGROUND

  • Ironson G, Gellman M, Spitzer S, Llabre M, Schneiderman N: Prediction of Ambulatory Blood Pressure as a Function of Laboratory Reactivity, Race, and Gender. Society of Behavioral Medicine, 1987

    BACKGROUND

  • Laperriere AR, VanDercar DH, Shyu LY, Ward MF, McCabe PM, Perry AC, Mosher PE, Schneiderman N. Microcomputer servo-controlled bicycle ergometer system for psychophysiological research. Psychophysiology. 1989 Mar;26(2):201-7. doi: 10.1111/j.1469-8986.1989.tb03157.x.

    PMID: 2727222BACKGROUND

  • Llabre MM, Ironson GH, Spitzer SB, Gellman MD, Weidler DJ, Schneiderman N. How many blood pressure measurements are enough? An application of generalizability theory to the study of blood pressure reliability. Psychophysiology. 1988 Jan;25(1):97-106. doi: 10.1111/j.1469-8986.1988.tb00967.x. No abstract available.

    PMID: 3353490BACKGROUND

  • Schneiderman N, McCabe, PM: Psychophysiologic Strategies in Laboratory Research. In: Schneiderman N, Kaufmann P, Weiss SM (Eds), Handbook of Research Methods in Cardiovascular Behavioral Medicine. Plenum Press, New York, 1988

    BACKGROUND

  • Llabre MM, Ironson GH, Spitzer SB, Gellman MD, Weidler DJ, Schneiderman N. Blood pressure stability of normotensives and mild hypertensives in different settings. Health Psychol. 1988;7 Suppl:127-37. doi: 10.1037/h0090276.

    PMID: 3243218BACKGROUND

  • VanDercar DH, Laperriere AR, Shyu LY, Ward MF, McCabe PM, Perry A, Schneiderman N. Microcomputer automated system for measuring systolic time intervals in response to exercise and a psychophysiological task. Psychophysiology. 1988 Nov;25(6):703-11. doi: 10.1111/j.1469-8986.1988.tb01912.x. No abstract available.

    PMID: 3241858BACKGROUND

  • Ironson GH, Gellman MD, Spitzer SB, Llabre MM, De Carlo Pasin R, Weidler DJ, Schneiderman N. Predicting home and work blood pressure measurements from resting baselines and laboratory reactivity in black and white Americans. Psychophysiology. 1989 Mar;26(2):174-84. doi: 10.1111/j.1469-8986.1989.tb03151.x.

    PMID: 2727219BACKGROUND

  • Tischenkel NJ, Saab PG, Schneiderman N, Nelesen RA, Pasin RD, Goldstein DA, Spitzer SB, Woo-Ming R, Weidler DJ. Cardiovascular and neurohumoral responses to behavioral challenge as a function of race and sex. Health Psychol. 1989;8(5):503-24. doi: 10.1037//0278-6133.8.5.503.

    PMID: 2698349BACKGROUND

  • Durel LA, Carver CS, Spitzer SB, Llabre MM, Weintraub JK, Saab PG, Schneiderman N. Associations of blood pressure with self-report measures of anger and hostility among black and white men and women. Health Psychol. 1989;8(5):557-75. doi: 10.1037//0278-6133.8.5.557.

    PMID: 2630294BACKGROUND

  • Saab PG, Llabre MM, Hurwitz BE, Frame CA, Reineke LJ, Fins AI, McCalla J, Cieply LK, Schneiderman N. Myocardial and peripheral vascular responses to behavioral challenges and their stability in black and white Americans. Psychophysiology. 1992 Jul;29(4):384-97. doi: 10.1111/j.1469-8986.1992.tb01712.x.

    PMID: 1410171BACKGROUND

  • Schneiderman N. Ethnicity and ambulatory blood pressure measurement: relationship to clinic and laboratory measurements. J Clin Pharmacol. 1992 Jul;32(7):604-9. doi: 10.1002/j.1552-4604.1992.tb05768.x.

    PMID: 1639997BACKGROUND

  • Spitzer SB, Llabre MM, Ironson GH, Gellman MD, Schneiderman N. The influence of social situations on ambulatory blood pressure. Psychosom Med. 1992 Jan-Feb;54(1):79-86. doi: 10.1097/00006842-199201000-00010.

    PMID: 1553403BACKGROUND

  • Llabre MM, Spitzer SB, Saab PG, Ironson GH, Schneiderman N. The reliability and specificity of delta versus residualized change as measures of cardiovascular reactivity to behavioral challenges. Psychophysiology. 1991 Nov;28(6):701-11. doi: 10.1111/j.1469-8986.1991.tb01017.x.

    PMID: 1816598BACKGROUND

  • Peckerman A, Saab PG, McCabe PM, Skyler JS, Winters RW, Llabre MM, Schneiderman N. Blood pressure reactivity and perception of pain during the forehead cold pressor test. Psychophysiology. 1991 Sep;28(5):485-95. doi: 10.1111/j.1469-8986.1991.tb01985.x.

    PMID: 1758926BACKGROUND

  • Gellman M, Spitzer S, Ironson G, Llabre M, Saab P, DeCarlo Pasin R, Weidler DJ, Schneiderman N. Posture, place, and mood effects on ambulatory blood pressure. Psychophysiology. 1990 Sep;27(5):544-51. doi: 10.1111/j.1469-8986.1990.tb01972.x.

    PMID: 2274617BACKGROUND

  • Donahue RP, Skyler JS, Schneiderman N, Prineas RJ. Hyperinsulinemia and elevated blood pressure: cause, confounder, or coincidence? Am J Epidemiol. 1990 Nov;132(5):827-36. doi: 10.1093/oxfordjournals.aje.a115725. No abstract available.

    PMID: 2239897BACKGROUND

  • Peckerman A, Hurwitz BE, Saab PG, Llabre MM, McCabe PM, Schneiderman N. Stimulus dimensions of the cold pressor test and the associated patterns of cardiovascular response. Psychophysiology. 1994 May;31(3):282-90. doi: 10.1111/j.1469-8986.1994.tb02217.x.

    PMID: 8008792BACKGROUND

  • Hurwitz BE, Nelesen RA, Saab PG, Nagel JH, Spitzer SB, Gellman MD, McCabe PM, Phillips DJ, Schneiderman N. Differential patterns of dynamic cardiovascular regulation as a function of task. Biol Psychol. 1993 Aug;36(1-2):75-95. doi: 10.1016/0301-0511(93)90082-j.

    PMID: 8218626BACKGROUND

  • Hurwitz BE, Shyu LY, Lu CC, Reddy SP, Schneiderman N, Nagel JH. Signal fidelity requirements for deriving impedance cardiographic measures of cardiac function over a broad heart rate range. Biol Psychol. 1993 Aug;36(1-2):3-21. doi: 10.1016/0301-0511(93)90076-k.

    PMID: 8218621BACKGROUND

  • Durel LA, Kus LA, Anderson NB, McNeilly M, Llabre MM, Spitzer S, Saab PG, Efland J, Williams R, Schneiderman N. Patterns and stability of cardiovascular responses to variations of the cold pressor test. Psychophysiology. 1993 Jan;30(1):39-46. doi: 10.1111/j.1469-8986.1993.tb03203.x.

    PMID: 8416061BACKGROUND

  • Llabre MM, Saab PG, Hurwitz BE, Schneiderman N, Frame CA, Spitzer S, Phillips D. The stability of cardiovascular parameters under different behavioral challenges: one-year follow-up. Int J Psychophysiol. 1993 May;14(3):241-8. doi: 10.1016/0167-8760(93)90038-q.

    PMID: 8340242BACKGROUND

  • Saab PG, Llabre MM, Hurwitz BE, Schneiderman N, Wohlgemuth W, Durel LA, Massie C, Nagel J. The cold pressor test: vascular and myocardial response patterns and their stability. Psychophysiology. 1993 Jul;30(4):366-73. doi: 10.1111/j.1469-8986.1993.tb02058.x.

    PMID: 8327622BACKGROUND

  • Schriefers KH. [Mechanical ileus]. Chirurg. 1975 Feb;46(2):49-53. No abstract available. German.

    PMID: 1120430BACKGROUND

  • Saab PG, Llabre MM, Schneiderman N, Hurwitz BE, McDonald PG, Evans J, Wohlgemuth W, Hayashi P, Klein B. Influence of ethnicity and gender on cardiovascular responses to active coping and inhibitory-passive coping challenges. Psychosom Med. 1997 Jul-Aug;59(4):434-46. doi: 10.1097/00006842-199707000-00014.

    PMID: 9251164BACKGROUND

  • Goldstein RZ, Hurwitz BE, Llabre MM, Schneiderman N, Gutt M, Skyler JS, Prineas RJ, Donahue RP. Modeling preclinical cardiovascular risk for use in epidemiologic studies: Miami community health study. Am J Epidemiol. 2001 Oct 15;154(8):765-76. doi: 10.1093/aje/154.8.765.

    PMID: 11590090BACKGROUND

  • Kline KA, Saab PG, Llabre MM, Spitzer SB, Evans JD, McDonald PA, Schneiderman N. Hemodynamic response patterns: responder type differences in reactivity and recovery. Psychophysiology. 2002 Nov;39(6):739-46. doi: 10.1111/1469-8986.3960739.

    PMID: 12462502BACKGROUND

  • La Greca AM, Bearman KJ. The diabetes social support questionnaire-family version: evaluating adolescents' diabetes-specific support from family members. J Pediatr Psychol. 2002 Dec;27(8):665-76. doi: 10.1093/jpepsy/27.8.665.

    PMID: 12403857BACKGROUND

  • Llabre MM, Spitzer SB, Saab PG, Schneiderman N. Piecewise latent growth curve modeling of systolic blood pressure reactivity and recovery from the cold pressor test. Psychophysiology. 2001 Nov;38(6):951-60. doi: 10.1111/1469-8986.3860951.

    PMID: 12240671BACKGROUND

  • Bearman KJ, La Greca AM. Assessing friend support of adolescents' diabetes care: the diabetes social support questionnaire-friends version. J Pediatr Psychol. 2002 Jul-Aug;27(5):417-28. doi: 10.1093/jpepsy/27.5.417.

    PMID: 12058006BACKGROUND

  • Peckerman A, Hurwitz BE, Nagel JH, Leitten C, Agatston AS, Schneiderman N. Effects of gender and age on the cardiac baroreceptor reflex in hypertension. Clin Exp Hypertens. 2001 Nov;23(8):645-56. doi: 10.1081/ceh-100107394.

    PMID: 11728009BACKGROUND

  • Hurwitz BE, Klimas NG, Llabre MM, Maher KJ, Skyler JS, Bilsker MS, McPherson-Baker S, Lawrence PJ, Laperriere AR, Greeson JM, Klaus JR, Lawrence R, Schneiderman N. HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure. Cardiovasc Toxicol. 2004;4(3):303-16. doi: 10.1385/ct:4:3:303.

    PMID: 15470277BACKGROUND

  • Llabre MM, Spitzer S, Siegel S, Saab PG, Schneiderman N. Applying latent growth curve modeling to the investigation of individual differences in cardiovascular recovery from stress. Psychosom Med. 2004 Jan-Feb;66(1):29-41. doi: 10.1097/01.psy.0000107886.51781.9c.

    PMID: 14747635BACKGROUND

  • Williams RB, Barefoot JC, Schneiderman N. Psychosocial risk factors for cardiovascular disease: more than one culprit at work. JAMA. 2003 Oct 22;290(16):2190-2. doi: 10.1001/jama.290.16.2190. No abstract available.

    PMID: 14570955BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Officials

  • Neil Schneiderman

    University of Miami

Study Design

Study Type
observational
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

July 1, 1986

Primary Completion

June 1, 2006

Study Completion

June 1, 2006

Last Updated

January 15, 2016

Record last verified: 2016-01