Magnetic Resonance Imaging Studies of Motor and Thought Processes

NCT00001361 | Completed

• 2 other identifiers: 93001093-N-0010
• Study Type: observational
• Target: 610
• Locations: 1 country
• Sites: 1

Brief Summary

Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation). MRI is especially useful when studying the brain, because it can provide information about certain brain functions. In addition, MRI is much better than standard X-rays at showing areas of the brain close to the skull and detecting changes in the brain associated with neurological diseases. In this study researchers will use MRI to gather information about the processes that control human movement and sensory processing. The purpose of the study is to investigate how the brain is activated when remembering, thinking, or recognizing objects. Researchers would like to determine what happens to brain functions when patients have trouble remembering, thinking, or recognizing objects following the start of disorders in the brain and nervous system. In addition, this study will investigate the processes of motor control in healthy volunteers and patients with disease.

Conditions

Cerebrovascular Disorder; Healthy; Movement Disorder; Nervous System Disease; Spinal Cord Injury

Keywords

Movement Disorders; Sensory Processing; Stroke; Spinal Cord Injury; Blood Flow; Blood Volume; Cognitive Function; Neurobehavioral Deficits; Neurological Disorders; Magnetic Resonance Imaging; Plasticity; Normal Volunteer

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

Patients with movement disorder and normal volunteers.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• National Institute of Neurological Disorders and Stroke (NINDS): lead

Study Sites (1)

National Institute of Neurological Disorders and Stroke (NINDS)

Bethesda, Maryland, 20892, United States

Location

Related Publications (3)

• Sadato N, Ibanez V, Campbell G, Deiber MP, Le Bihan D, Hallett M. Frequency-dependent changes of regional cerebral blood flow during finger movements: functional MRI compared to PET. J Cereb Blood Flow Metab. 1997 Jun;17(6):670-9. doi: 10.1097/00004647-199706000-00008.

  PMID: 9236723 BACKGROUND

• Karni A, Meyer G, Jezzard P, Adams MM, Turner R, Ungerleider LG. Functional MRI evidence for adult motor cortex plasticity during motor skill learning. Nature. 1995 Sep 14;377(6545):155-8. doi: 10.1038/377155a0.

  PMID: 7675082 BACKGROUND

• Aquilonius SM. What has PET told us about Parkinson's disease? Acta Neurol Scand Suppl. 1991;136:37-9. doi: 10.1111/j.1600-0404.1991.tb05018.x.

  PMID: 1801535 BACKGROUND

MeSH Terms

Conditions

Cerebrovascular Disorders; Movement Disorders; Nervous System Diseases; Spinal Cord Injuries; Stroke

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Spinal Cord Diseases; Trauma, Nervous System; Wounds and Injuries

Study Design

• Study Type: observational
• Sponsor Type: NIH

Study Record Dates

• First Submitted: November 3, 1999
• First Posted: November 4, 1999
• Study Start: October 1, 1992
• Study Completion: January 1, 2002
• Last Updated: March 4, 2008

Record last verified: 2002-01

Locations

US (1)