Diagnosis and History Study of Patients With Different Neurological Conditions

NCT00001367 | Completed

• 2 other identifiers: 93020293-N-0202
• Study Type: observational
• Target: 3,813
• Locations: 1 country
• Sites: 1

Brief Summary

This protocol is a screening and natural history protocol, which allows for evaluation of patients and families where neurological conditions are present for enrollment into other studies and will also be used to screen healthy volunteers to create a pool of potential future HV matches for HMCS protocols. Through diagnostic evaluations, data will be collected for research use in this study.

Conditions

Nervous System Disease; Healthy Volunteer

Keywords

Healthy Volunteer; Nervous System Disease; Natural History

Outcome Measures

Primary Outcomes (1)

• to screen patients with neurological conditions and family members of patients with neurological conditions for enrollment in additional research protocols

  The goal is to screen patients with neurological conditions and family members of patients with neurological conditions for enrollment in additional research protocols. No investigational treatments will be administered on this protocol and the NIH physicians will be playing a consultative role to the patient s primary physician.

  ongoing

Study Arms (3)

family members

Family Members who are 2 years old or older of people with a neurological disorder

healthy volunteers

healthy volunteers age 18 and older

patients

subjects with neurological disorders who are 2 years old or older

Eligibility Criteria

• Age: 2 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The following population groups may participate: - Subjects with neurological disorders who are 2 years old or older, - Family members who are 2 years old or older of people with a neurological disorder, - Healthy volunteers who are 18 years old or older.

You may qualify if:

• Patients with neurological disorders and subjects with a family history of neurological conditions OR
• Healthy volunteers: People age 18 or older who are generally in good health.

You may not qualify if:

• Patients \<2 years old.
• Employees of HMCS in NINDS.

Sponsors & Collaborators

• National Institute of Neurological Disorders and Stroke (NINDS): lead

Study Sites (1)

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

Location

Related Links

• NIH Clinical Center Detailed Web Page

MeSH Terms

Conditions

Nervous System Diseases

Study Officials

• Debra J Ehrlich, M.D.

  National Institute of Neurological Disorders and Stroke (NINDS)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 3, 1999
• First Posted: November 4, 1999
• Study Start: September 30, 1993
• Last Updated: March 31, 2026

Record last verified: 2025-11-07

Locations

US (1)