AVF Awareness Among Advanced CKD Patients

NCT07817953 | Not Yet Recruiting

• 1 other identifier: AVF-Awareness-CKD-Assiut-2026
• Study Type: observational
• Target: 116
• Locations: 0 countries
• Sites: N/A

Brief Summary

This cross-sectional study aims to assess awareness regarding arteriovenous fistula creation among patients with advanced chronic kidney disease, including pre-dialysis patients and those receiving maintenance hemodialysis, at Assiut University Hospital.

Conditions

Dialysis; Complications; Arteriovenous Fistula; Chronic Kidney Diseases; Kidney Failure, Chronic

Keywords

Arteriovenous fistula; AVF awareness; Hemodialysis; Chronic kidney disease; Vascular access; Assiut

Outcome Measures

Primary Outcomes (1)

• Pre-dialysis AVF awareness score

  Mean score of knowledge regarding arteriovenous fistula creation (including its use for hemodialysis, need for pre-dialysis preparation, maturation time, arm protection, and differences from catheter) assessed by a structured questionnaire. For patients already on maintenance hemodialysis, awareness will be assessed retrospectively for the period before dialysis initiation.

  Baseline

Secondary Outcomes (5)

• Proportion with prior AVF counseling

  Baseline

• Vascular access used at first hemodialysis session

  Baseline

• Timing of AVF creation

  Baseline

• Willingness to undergo AVF creation

  Baseline

• Sources of AVF information

  Baseline

Study Arms (1)

Single cohort: Adults with advanced CKD

Adults with advanced chronic kidney disease (pre-dialysis stage 4-5 and maintenance hemodialysis patients) who will complete a structured questionnaire assessing awareness of arteriovenous fistula creation.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with advanced chronic kidney disease (CKD stage 4-5 not on maintenance hemodialysis or currently receiving maintenance hemodialysis) attending the Nephrology Unit and Maintenance Hemodialysis Unit of Assiut University Hospital.

You may qualify if:

• Age 18 years or older
• Documented chronic kidney disease
• CKD stage 4-5 not on maintenance hemodialysis OR currently on maintenance hemodialysis for established CKD
• Able to understand and answer the questionnaire
• Written informed consent

You may not qualify if:

• Acute kidney injury without established CKD
• Previous kidney transplantation (if considered to affect homogeneity)
• Severe cognitive or communication impairment preventing reliable questionnaire completion
• Unable or unwilling to provide informed consent
• Inability to provide reasonably reliable information about the pre-dialysis period (for retrospective questions)

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Yuan S, Hu D, Gao D, Butch CJ, Wang Y, Zheng H, Sheng Z. Recent advances of engineering cell membranes for nanomedicine delivery across the blood-brain barrier. J Nanobiotechnology. 2025 Jul 8;23(1):493. doi: 10.1186/s12951-025-03572-y.

  PMID: 40624508 BACKGROUND

• Cavanaugh KL, Wingard RL, Hakim RM, Elasy TA, Ikizler TA. Patient dialysis knowledge is associated with permanent arteriovenous access use in chronic hemodialysis. Clin J Am Soc Nephrol. 2009 May;4(5):950-6. doi: 10.2215/CJN.04580908. Epub 2009 Apr 23.

  PMID: 19389825 BACKGROUND

• Shamasneh AO, Atieh AS, Gharaibeh KA, Hamadah A. Perceived barriers and attitudes toward arteriovenous fistula creation and use in hemodialysis patients in Palestine. Ren Fail. 2020 Nov;42(1):343-349. doi: 10.1080/0886022X.2020.1748650.

  PMID: 32338112 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Arteriovenous Fistula; Kidney Failure, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Arteriovenous Malformations; Vascular Malformations; Cardiovascular Abnormalities; Cardiovascular Diseases; Vascular Fistula; Vascular Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Fistula; Pathological Conditions, Anatomical

Study Officials

• Mohamed A Abozaid, prof

  Internal Medicine Department, Assiut University Hospitals

  STUDY CHAIR

Central Study Contacts

Boliss s Ragheb, Resident

CONTACT

+201003957926; Poles18313386@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Physician

Study Record Dates

• First Submitted: September 9, 2026
• First Posted: September 14, 2026
• Study Start: September 10, 2026
• Primary Completion (Estimated): September 10, 2027
• Study Completion (Estimated): February 20, 2028
• Last Updated: September 14, 2026

Record last verified: 2026-09