Mucocutaneous Manifestations in Patients With Chronic Kidney Disease inNewVally and Assuit;Hospital Based Study

NCT05819320 | Not Yet Recruiting

• 1 other identifier: skin manifestations in CKD
• Study Type: observational
• Target: 140
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.To study the patterns of mucocutaneous disorders in Chronic Kidney Disease patients in Eldakhla General Hospital, New Valley and in Assiut University hospital .
2. 2.Comparison of the patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease in renal unit of internal medicine of Eldakhla general hospital in New Vally and pediatric and adult renal units of Assuit university hospital .

Conditions

Chronic Kidney Diseases; Manifestation, Skin

Outcome Measures

Primary Outcomes (1)

• study the patterns of mucocutaneous disorders in Chronic Kidney Disease patients in Eldakhla General Hospital, New Valley and in Assiut University hospital

  Comparison of the patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease in renal unit of internal medicine of Eldakhla general hospital in New Vally and pediatric and adult renal units of Assuit university hospital .

  Base line

Study Arms (3)

ALdakhla general hospital patients

patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease in renal unit of internal medicine of Eldakhla general hospital in New Vally

Other: observe pattern of mucocutaneous manifestations in chronic kidney disease patients

Assuit University hospital adult renal unit

patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease in renal unit of internal medicine of Assuit University hospital (adult renal unit ) .

Other: observe pattern of mucocutaneous manifestations in chronic kidney disease patients

Assuit University hospital pediatric renal unit

patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease in renal unit of internal medicine of Assuit University hospital (pediatric renal unit ).

Other: observe pattern of mucocutaneous manifestations in chronic kidney disease patients

Interventions

observe pattern of mucocutaneous manifestations in chronic kidney disease patients OTHER

1. To study the patterns of mucocutaneous disorders in Chronic Kidney Disease patients . 2. Comparison of the patterns of mucocutaneous manifestations and their correlation with the different stages of Chronic Kidney Disease

ALdakhla general hospital patients; Assuit University hospital adult renal unit; Assuit University hospital pediatric renal unit

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients with chronic kidney disease attending the renal unit of internal medicine of Eldakhla General hospital, New Vally ,and Assiut University hospital will be included in this study . Detailed medical history, clinical examination and investigations which support the diagnosis will be recorded including: urine analysis, CBC, Blood urea, creatinine , x- ray, arterial blood gases , abdominal sonography ,serum electrolytes, multislice CT KUB , Demsa scan ......etc . Potassium hydroxide (KOH) mounts, skin biopsy, Gram's, and Giemsa staining, and bacterial or fungal cultures will be performed when we need.

You may qualify if:

• All patients with chronic kidney disease attending the renal unit of internal medicine of Eldakhla General hospital, New Vally ,and Assiut University hospital will be included in this study within two years and will be examined for any skin manifestations and mucocutaneous findings.

You may not qualify if:

• \- Human immunodeficiency (HIV) affected persons, renal transplant recipients, and patients with acute renal failure, hepatobiliary, pancreatic, or thyroid disorders, cutaneous or systemic malignancies will be excluded.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Schonmann Y, Mansfield KE, Mulick A, Roberts A, Smeeth L, Langan SM, Nitsch D. Inflammatory skin diseases and the risk of chronic kidney disease: population-based case-control and cohort analyses. Br J Dermatol. 2021 Oct;185(4):772-780. doi: 10.1111/bjd.20067. Epub 2021 Jun 6.

  PMID: 33730366 BACKGROUND

• Rashpa RS, Mahajan VK, Kumar P, Mehta KS, Chauhan PS, Rawat R, Sharma V. Mucocutaneous Manifestations in Patients with Chronic Kidney Disease: A Cross-sectional Study. Indian Dermatol Online J. 2018 Jan-Feb;9(1):20-26. doi: 10.4103/idoj.IDOJ_160_17.

  PMID: 29441293 BACKGROUND

• Galperin TA, Cronin AJ, Leslie KS. Cutaneous manifestations of ESRD. Clin J Am Soc Nephrol. 2014 Jan;9(1):201-18. doi: 10.2215/CJN.05900513. Epub 2013 Oct 10.

  PMID: 24115194 BACKGROUND

• Goel V, Sil A, Das A. Cutaneous Manifestations of Chronic Kidney Disease, Dialysis and Post-Renal Transplant: A Review. Indian J Dermatol. 2021 Jan-Feb;66(1):3-11. doi: 10.4103/ijd.IJD_502_20.

  PMID: 33911288 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Skin Manifestations

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• Doaa Samir sayed

  Supervisor

  STUDY DIRECTOR

• Eman Mohammed kamal Elsayed Yousef

  Supervisor

  STUDY DIRECTOR

• Marwa Hassan Mohammed

  Investigator

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Marwa Hassan Mohammed, M,B,B,CH

CONTACT

01224456778; marwahassan99956@gmail.com

Marwa Hassan Mohammed, Resident

CONTACT

01224456778; marwahassan99956@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 2 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr Marwa Hassan Mohammed

Study Record Dates

• First Submitted: April 6, 2023
• First Posted: April 19, 2023
• Study Start: June 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: April 1, 2025
• Last Updated: April 17, 2024

Record last verified: 2024-04