Effect of an Antioxidant Dietary Supplement on Skin Radiance
Randomized Double-Blind Placebo-Controlled Trial Evaluating the Effect of an Oral Antioxidant Dietary Supplement on Skin Radiance in Women Exposed to Urban Air Pollution
1 other identifier
interventional
60
1 country
1
Brief Summary
A randomized, double-blind, placebo-controlled study evaluating the effects of an oral antioxidant dietary supplement on skin radiance in women exposed to urban air pollution. Secondary assessments include skin tone homogeneity, pigmentation, inflammation, skin barrier function, glycation markers.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Sep 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 31, 2026
CompletedFirst Posted
Study publicly available on registry
August 28, 2026
CompletedStudy Start
First participant enrolled
September 1, 2026
ExpectedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2026
Study Completion
Last participant's last visit for all outcomes
December 1, 2026
August 28, 2026
July 1, 2026
3 months
July 31, 2026
August 25, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Skin Radiance
Glossymeter
Day 0 and Day 90
Secondary Outcomes (7)
Skin Radiance
Day 0 and Day 30
Skin Radiance
Day 0, Day 30, Day 90
Skin homogeneity
Day 0, Day 30, Day 90
Skin homogeneity
Day 0, Day 30, Day 90
TransEpidermal Water Loss
Day 0, Day 30, Day 90
- +2 more secondary outcomes
Study Arms (2)
Dietary supplement : Placebo
PLACEBO COMPARATORMaltodextrin = 400 mg/capsule, 1 capsule per day.
Dietary supplement : Investigational product
ACTIVE COMPARATOR1 capsule contains :140 mg Rosa damascena extract, 20 mg melon concentrate and 140 mg acerola extract; 57mg maltodextrin; 1 capsule per day.
Interventions
Oral antioxidant dietary supplement administered as one capsule once daily for 90 days.
Placebo dietary supplement administered as one capsule once daily for 90 days.
Eligibility Criteria
You may qualify if:
- Healthy female aged 35 to 65 years
- Fitzpatrick skin phototype II to IV
- All skin types
- Dull and uneven skin tone
- Living in an urban environment and exposed to air pollution
- Able to comply with study procedures
- Written informed consent provided
You may not qualify if:
- Pregnant or breastfeeding
- Current use of dietary supplements or vitamin supplements
- Specific dietary restrictions
- Unstable medication affecting water retention
- Active medical disease
- Facial dermatological disorder
- Participation in another clinical trial
- Vulnerable populations according to French regulations
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Robertet SAlead
Study Sites (1)
Gredeco
Paris, 75 013, France
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 31, 2026
First Posted
August 28, 2026
Study Start (Estimated)
September 1, 2026
Primary Completion (Estimated)
December 1, 2026
Study Completion (Estimated)
December 1, 2026
Last Updated
August 28, 2026
Record last verified: 2026-07