DoubleTake: Effect of Message Exposure Via a Discrete Choice Experiment With Eye-Tracking on Quit Attempts Among Adults Who Smoke Menthol Cigarettes

NCT07782879 | Not Yet Recruiting

• 2 other identifiers: H26621R01CA289552
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 2

Brief Summary

\<p\>The goal of this clinical trial is to learn how exposure to anti-smoking social media messages affects quitting-related behaviors. Eligible participants will be adults aged 21 or older who have used menthol cigarettes on at least 4 days during the past 30 days.\</p\> \<br\> \<p\>The main question this study aims to answer is: Does exposure to anti-smoking messages (in the context of a discrete choice experiment \[DCE\] with eye-tracking study) increase quitting-related behaviors over the following 2 weeks?\</p\> \<br\> \<p\>Participants will be randomly assigned to view the messages either immediately or after a 2-week waiting period, allowing researchers to compare quitting-related behaviors between the two groups. The primary outcome is whether participants report making a quit attempt in the 2 weeks following randomization.\</p\> \<br\> \<p\>Participants will:\</p\> \<ul\> \<li\>Complete eligibility screening and baseline questions about demographics and tobacco use.\</li\> \<li\>Be randomly assigned to view the messages immediately or after a 2-week waiting period.\</li\> \<li\>Attend a 1-hour in-person study visit at Georgia State University or the University of California, Santa Barbara.\</li\> \<li\>View 64 anti-smoking social media messages presented in 16 choice sets while their eye movements and pupil dilation are measured using a screen-based eye-tracking device.\</li\> \<li\>Select which messages most attract their attention, which they would be most likely to share, and which would most motivate them to quit smoking.\</li\> \<li\>Complete questions about quitting-related behaviors either during the study visit (waitlist control condition) or through an online questionnaire 2 weeks later (immediate condition).\</li\> \</ul\>

Conditions

Menthol Cigarettes; Smoking Behavior; Cigarette Use

Keywords

smoking; menthol cigarettes; menthol; health communication

Outcome Measures

Primary Outcomes (1)

• Quit attempts

  Self-reported quit attempt: Participants will be asked, "Have you made an attempt to quit smoking cigarettes in the past 2 weeks?" Response options will include yes, no, and don't know. Participants who report a quit attempt will be asked, "How long did you stop smoking?" with responses recorded as the number of days, ranging from less than 1 day to 14 days. Participants who report stopping smoking for 1 day or more will be classified as having made a quit attempt for the primary outcome analysis.

  2 weeks after message exposure for the immediate intervention arm and 2 weeks before message exposure for the waitlist control arm.

Secondary Outcomes (1)

• Intention to Quit

  2 weeks after message exposure for the immediate intervention arm and 2 weeks before message exposure for the waitlist control arm.

Study Arms (2)

DCE exposure

EXPERIMENTAL

Participants complete the in-person discrete choice experiment (DCE) with eye-tracking study visit immediately after randomization. During this visit, participants view 64 anti-smoking social media messages presented in 16 choice sets while their eye movements are recorded. Participants then complete an online questionnaire assessing quitting-related behaviors 2 weeks later.

Behavioral: Message Exposure via Discrete Choice Experiment

Waitlist Control

NO INTERVENTION

Participants wait 2 weeks following randomization. At the start of an in-person visit conducted at the end of this waiting period, participants answer questions about quitting-related behaviors covering the preceding 2-week waiting period. Participants then complete the discrete choice experiment (DCE) with eye-tracking study.

Interventions

Message Exposure via Discrete Choice Experiment BEHAVIORAL

Participants will view 64 anti-smoking social media messages, presented across 16 choice sets, in a discrete choice experiment (DCE) with eye-tracking. Within each choice set, participants indicate which message most attracts their attention, which they would be most likely to share or repost, and which would most motivate them to quit smoking.

DCE exposure

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 21+ years
• Smoked menthol cigarettes at least once a week in the past 30 days
• Can speak, read, and write in English
• Willing to participate in an in-person study

You may not qualify if:

• Eye conditions affecting fixation, ocular motility, or central acuity (e.g., strabismus, nystagmus, ptosis, aniridia, maculopathy, advanced cataracts, or other conditions affecting macular fixation or central visual acuity).
• Multifocal or near-infrared-blocking/heavily tinted corrective lenses: bifocal, trifocal, or progressive/varifocal lenses, or coatings that impair eye-tracking. (Single-vision glasses and contact lenses are eligible.)

Sponsors & Collaborators

• Georgia State University: lead
• University of California, Santa Barbara: collaborator
• National Cancer Institute (NCI): collaborator

Study Sites (2)

University of California, Santa Barbara

Santa Barbara, California, 93106, United States

Location

Georgia State University

Atlanta, Georgia, 30303, United States

Location

MeSH Terms

Conditions

Smoking

Condition Hierarchy (Ancestors)

Behavior

Central Study Contacts

Lyudmila Popova, Ph.D

CONTACT

404-413-9338; lpopova1@gsu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 30, 2026
• First Posted: August 24, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: August 24, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)