Popliteus Muscle Release Versus Patellofemoral Mobilization in Patellofemoral Pain Syndrome
PFPS
1 other identifier
interventional
48
0 countries
N/A
Brief Summary
This study will be conducted to compare the effect of popliteus muscle release and patellofemoral mobilization on pain intensity, function, and quadriceps muscle strength in patients with patellofemoral pain syndrome?
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jul 2026
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 7, 2026
CompletedFirst Posted
Study publicly available on registry
July 13, 2026
CompletedStudy Start
First participant enrolled
July 15, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 1, 2026
July 13, 2026
July 1, 2026
4 months
July 7, 2026
July 7, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
pain intensity
The scale used will be the visual analogue scale (VAS), which consists of a line, usually 10 cm long, the patient will be instructed to place a vertical mark on to indicate his/ her pain, ranging from no pain or discomfort (0), to the worst pain that could possibly feel
up to four weeks
Secondary Outcomes (2)
knee disability
up to four weeks
quadriceps muscle strength
up to four weeks
Study Arms (3)
Popliteus Muscle Release
EXPERIMENTALSixteen patients with patellofemoral pain syndrome will receive popliteus muscle release. plus traditional physical therapy three times a week for 4 weeks.
Patellofemoral Mobilization
EXPERIMENTALSixteen patients with patellofemoral pain syndrome will receive patellofemoral mobilization plus traditional physical therapy three times a week for 4 weeks.
traditional therapy
ACTIVE COMPARATORSixteen patients with patellofemoral pain syndrome will receive traditional physical therapy three times a week for 4 weeks.
Interventions
the participant will lie supine and relaxed on a treatment bench. The therapist will begin the treatment by flexing the participant's knee to approximately 15-25 degrees. Then, the therapist will apply pressure to the popliteus muscle while simultaneously extending the knee to approximately 5 degrees of flexion. When the knee is extended, the pressure will be released. The therapist will repeat this procedure for up to 2 minutes plus tradional therapy
Following the clinical guidelines established by Brukner and Khan, the mobilization will be performed with the patient in a supine position to ensure complete relaxation of the quadriceps musculature, thereby minimizing joint compressive forces. The intervention will include multidirectional glides tailored to specific functional deficits:Superior glides,Inferior glides,Medial-lateral excursions and tilt mobilization.Each mobilization will be applied as a gentle sustained glide for duration of 30 to 60 seconds per repetition
patients will receive quadriceps muscle strength, hip extension strength, hamstring stretch.
Eligibility Criteria
You may qualify if:
- Male and female participants aged 18-30 years.
- minimum history of 3 months of unilateral PFP.
- pain intensity score of ≥3 on a 10-cm Visual Analog Scale (VAS) for worst pain experienced during the previous week.
- Pain reproduced during at least two of the following functional activities: stair ascent or descent, running, hopping, prolonged sitting, squatting, or kneeling.
- Presence of pain on at least one of the following clinical tests: patellar compression test or palpation of the patellar facets.
You may not qualify if:
- Clinical, x-ray, or MRI findings indicative of other specific pathology including osteoarthritis, meniscal, ligament or cartilage injury, apophysitis.
- Recurrent patellar subluxation or dislocation.
- Cortisone use over an extended period of time.
- Previous surgery to the knee joint; trauma to the knee joint affecting the presenting clinical condition.
- Lower limb deformities.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Masking Details
- opaque sealed envelope
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principle investigator : mohamed abdelalim bahig
Study Record Dates
First Submitted
July 7, 2026
First Posted
July 13, 2026
Study Start
July 15, 2026
Primary Completion (Estimated)
November 1, 2026
Study Completion (Estimated)
November 1, 2026
Last Updated
July 13, 2026
Record last verified: 2026-07