Impact of a Targeted 8-Week Exercise Program on Pain Measures and Isokinetic Muscle Strength in Females With Patellofemoral Pain Syndrome

NCT06993350 | Completed

• 2 other identifiers: Faculty of Physical Therapyfaculty of physical therapy
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Patellofemoral pain syndrome (PFPS) is condition characterized by anterior knee pain that predominantly affects young and physically active females. The etiology of PFPS is multifactorial, involving biomechanical, muscular, and neuromuscular factors that contribute to altered patellar tracking and increased pain sensitivity.

Conditions

Patellofemoral Pain Syndrome

Keywords

Patellofemoral pain syndrome; weight-bearing pain; isokinetic strength

Outcome Measures

Primary Outcomes (1)

• pain intensity

  measured by Visual Analogue Scale. a score range from 0 to 10. 0 means no pain and 10 means severe pain

  two times of testing (before and 8 weeks after intervention)

Study Arms (2)

group A (patients with PFPS)

OTHER

patients receive specific weight bearing program known as weight bearing exercise for better balance program

Other: experimental group

control group

NO INTERVENTION

patient will not receive any intervention

Interventions

experimental group OTHER

eight weeks of targeted weight bearing program

Also known as: weight bearing program

group A (patients with PFPS)

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Eligible participants will present with clinically diagnosed anterior knee pain exacerbated by activities such as stair climbing, squatting, or prolonged sitting, with a pain duration of at least three months to ensure chronicity. All participants will possess adequate intellectual and cognitive abilities to comprehend and follow exercise instructions, and they will provide informed consent prior to enrollment.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, 12511, Egypt

Location

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr

Study Record Dates

• First Submitted: May 19, 2025
• First Posted: May 28, 2025
• Study Start: March 2, 2025
• Primary Completion: April 30, 2025
• Study Completion: April 30, 2025
• Last Updated: July 28, 2025

Record last verified: 2025-07

Locations

EG (1)