NCT07290296

Brief Summary

The aim of the current study is to compare the effect of popliteus muscle release and Kinesio taping on pain intensity, function, dynamic balance, and quadriceps muscle strength in patients with patellofemoral pain syndrome.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 5, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

December 18, 2025

Completed
23 days until next milestone

Study Start

First participant enrolled

January 10, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2026

Completed
Last Updated

January 14, 2026

Status Verified

January 1, 2026

Enrollment Period

3 months

First QC Date

December 5, 2025

Last Update Submit

January 13, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Pain intensity

    by visual analogue scale The visual analogue scale represents the pain range that a patient thinks they might experience. The line is typically 10 centimeters long, with anchor descriptors such as (in the pain context) "no pain" and "worst pain imaginable." The patient makes a mark reflecting his or her perception, and the distance from the left endpoint to the mark is measured in centimeters. Higher scores represent worse pain.

    It will be assessed at baseline and after 4 weeks.

  • Knee Function

    by kujala scale The Arabic Kujala Patellofemoral Disorder scale, also called the anterior knee pain scale, is composed of 13 multiple-choice questions, each contributing to a total score ranging from 0 to 100. A higher score indicates better knee function and less pain, while a lower score reflects greater pain and disability.

    It will be assessed at baseline and after 4 weeks.

  • Balance

    by Star Excursion Balance Test (SEBT)

    It will be assessed at baseline and after 4 weeks.

Secondary Outcomes (1)

  • Quadriceps Strength

    It will be assessed at baseline and after 4 weeks.

Study Arms (3)

Control Group

ACTIVE COMPARATOR

The control group will receive traditional physical therapy treatment at the painful anterior knee, which includes quadriceps strength, hip abduction strength, hip extension strength, hamstring stretch, and gait training.

Other: Traditional Physical Therapy Treatment

Study Group 1

ACTIVE COMPARATOR

Study group 1 will receive traditional treatment as the control group plus release to the popliteus muscle.

Other: Traditional Physical Therapy TreatmentOther: Popliteus Muscle Release

Study Group 2

ACTIVE COMPARATOR

Study group 2 will receive traditional treatment as the control group plus Kinesio tape on the popliteus muscle.

Other: Traditional Physical Therapy TreatmentOther: Kinesio Taping

Interventions

Myofascial release for the popliteus muscle

Study Group 1

Kinesio tape on the popliteus muscle

Study Group 2

Quadriceps strength, hip abduction strength, hip extension strength, hamstring stretch, gait training

Control GroupStudy Group 1Study Group 2

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients of both genders with an age range of 18-30 years old.
  • minimum 3-month history of patellofemoral pain.
  • a pain score for worst pain intensity during the previous week of 3 or more on a Visual Analog Scale (0-10, most pain).
  • reproduced by at least two of the following activities: Stair ascent or descent, hopping, running, prolonged sitting, squatting, or kneeling and present on at least one of the following clinical tests: Compression of the patella or palpation of the patellar facets.

You may not qualify if:

  • Clinical, x-ray, or MRI findings indicative of other specific pathology, including osteoarthritis, meniscal, ligament, or cartilage injury, or apophysitis.
  • recurrent patellar subluxation or dislocation.
  • cortisone use over an extended period of time.
  • previous surgery to the knee joint; trauma to the knee joint affecting the presenting clinical condition.
  • physiotherapy or other similar exercises for patellofemoral pain syndrome within the previous 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Suez

Suez, Egypt

RECRUITING

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Officials

  • Hafsa He Abdullah, MSc

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hafsa He Abdullah, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physical Therapist, MSc in Physical Therapy, Cairo University

Study Record Dates

First Submitted

December 5, 2025

First Posted

December 18, 2025

Study Start

January 10, 2026

Primary Completion

April 1, 2026

Study Completion

April 1, 2026

Last Updated

January 14, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations