Comparison of Different Chest Compression Techniques in Infant Resuscitation

NCT07698340 | Completed

• 1 other identifier: ASH2
• Study Type: interventional
• Target: 116
• Locations: 1 country
• Sites: 1

Brief Summary

In this prospective, single-center, randomized, self-controlled crossover manikin simulation study, participitants performed 2 minutes of single-rescuer CPR (30:2 compression-to-ventilation ratio) with each of the four techniques (the two-finger (2F), three-finger (3F), heel-of-one-hand (HOH), and two-thumb (2T) techniques) in a randomized order, with at least 10 minutes of rest between techniques. Chest compression depth, rate, release velocity, and the proportion of compressions within the target range were recorded using a feedback device. Provider fatigue and perceived difficulty (modified Borg scale) were assessed as secondary outcomes

Conditions

Resuscitation; Cardiac Arrest (CA)

Keywords

Cardiopulmonary Resuscitation; manikin; pediatric; advanced cardiac life support methods

Outcome Measures

Primary Outcomes (4)

• Mean Chest Compression Depth

  Measured in centimeters (cm) using a CPR feedback device.

  2 minutes of CPR application

• Mean Chest Compression Rate

  Measured as compressions per minute

  2 minutes of CPR application

• Chest Compression Release Velocity

  Measured in millimeters per second (mm/s)

  2 minutes of CPR application

• Compressions Within Target Range

  Percentage of compressions performed within the target range.

  2 minutes of CPR application

Secondary Outcomes (2)

• Provider Fatigue

  During the 2-minute CPR application

• Perceived Difficulty

  Assessed immediately after each 2-minute application.

Study Arms (4)

Two-Finger (2F) Technique

EXPERIMENTAL

Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-finger technique with a 30:2 compression-to-ventilation ratio.

Procedure: Two-Finger (2F) Technique

Three-Finger (3F) Technique

EXPERIMENTAL

Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the three-finger technique with a 30:2 compression-to-ventilation ratio.

Procedure: Three-Finger (3F) Technique

Heel-of-One-Hand (HOH) Technique

EXPERIMENTAL

Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the heel-of-one-hand technique with a 30:2 compression-to-ventilation ratio.

Procedure: Heel-of-One-Hand (HOH) Technique

Two-Thumb (2T) Technique

EXPERIMENTAL

Participants performed single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-thumb technique with a 30:2 compression-to-ventilation ratio.

Procedure: Two-Thumb (2T) Technique

Interventions

Two-Finger (2F) Technique PROCEDURE

Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-finger chest compression technique with a 30:2 compression-to-ventilation ratio

Two-Finger (2F) Technique

Three-Finger (3F) Technique PROCEDURE

Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the three-finger chest compression technique with a 30:2 compression-to-ventilation ratio.

Three-Finger (3F) Technique

Heel-of-One-Hand (HOH) Technique PROCEDURE

Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the heel-of-one-hand chest compression technique with a 30:2 compression-to-ventilation ratio.

Heel-of-One-Hand (HOH) Technique

Two-Thumb (2T) Technique PROCEDURE

Participants perform single-rescuer basic life support CPR on an infant manikin for 2 minutes using the two-thumb chest compression technique with a 30:2 compression-to-ventilation ratio.

Two-Thumb (2T) Technique

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Resident physicians working in the Emergency Medicine Clinic of Ankara Bilkent City Hospital.
• Voluntary agreement to participate in the study.

You may not qualify if:

• Presence of a musculoskeletal disorder or disability that could interfere with CPR performance.
• Unwillingness to participate.

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

AnkaraCHBilkent

Ankara, Turkey (Türkiye)

Location

Related Publications (2)

• Joyner BL Jr, Dewan M, Bavare A, de Caen A, DiMaria K, Donofrio-Odmann J, Fosse G, Haskell S, Mahgoub M, Meckler G, Requist J, Schexnayder SM, Olech Smith M, Werho D, Raymond TT. Part 6: Pediatric Basic Life Support: 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2025 Oct 21;152(16_suppl_2):S424-S447. doi: 10.1161/CIR.0000000000001370. Epub 2025 Oct 22.

  PMID: 41122891 BACKGROUND

• Kleinman ME, de Caen AR, Chameides L, Atkins DL, Berg RA, Berg MD, Bhanji F, Biarent D, Bingham R, Coovadia AH, Hazinski MF, Hickey RW, Nadkarni VM, Reis AG, Rodriguez-Nunez A, Tibballs J, Zaritsky AL, Zideman D; Pediatric Basic and Advanced Life Support Chapter Collaborators. Part 10: Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2010 Oct 19;122(16 Suppl 2):S466-515. doi: 10.1161/CIRCULATIONAHA.110.971093.

  PMID: 20956258 BACKGROUND

MeSH Terms

Conditions

Heart Arrest

Interventions

Methods

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 7, 2026
• First Posted: July 13, 2026
• Study Start: January 1, 2024
• Primary Completion: January 1, 2025
• Study Completion: January 1, 2025
• Last Updated: July 13, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: SAP
• Time Frame: Data will become available immediately following the publication of the article and will be permanently accessible.
• Access Criteria: The data is openly accessible in the Mendeley Data repository.

Locations

TU (1)