Clinical Evaluation of Prefabricated Versus 3D-Printed Composite Resin Veneers: in Vivo Study
1 other identifier
interventional
40
1 country
1
Brief Summary
The purpose of this study is to clinically evaluate prefabricated versus 3D-printed composite resin veneers
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2025
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 25, 2025
CompletedFirst Submitted
Initial submission to the registry
July 2, 2026
CompletedFirst Posted
Study publicly available on registry
July 9, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 26, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
April 29, 2027
July 9, 2026
July 1, 2026
2 years
July 2, 2026
July 2, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Color match and stability
Clinical evaluation of color match and color stability will be performed according to the World Dental Federation (FDI) evaluation criteria by two calibrated evaluators at baseline and at 6, 9, 12, and 24 months. Veneer restorations will be assigned FDI scores ranging from 1 (clinically excellent) to 5 (clinically poor). Clinical success will be considered as scores of 1-3 and failure as scores of 4-5. Assessment will be carried out under standardized lighting conditions using visual examination and magnification. Statistical analysis will be performed to compare changes over time and between the two study groups.
24 months
Study Arms (2)
Prefabricated Composite Resin Veneers
EXPERIMENTALParticipants received prefabricated composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were placed according to the manufacturer's instructions using a standardized adhesive protocol.
3D-Printed Composite Resin Veneers
EXPERIMENTALParticipants received customized 3D-printed composite resin veneer restorations for the treatment of anterior teeth requiring esthetic rehabilitation. Veneers were fabricated using a digital workflow and cemented according to the manufacturer's instructions using a standardized adhesive protocol
Interventions
Prefabricated composite resin veneer restorations used for esthetic rehabilitation of anterior teeth. Restorations will be bonded following the manufacturer's recommended adhesive protocol.
Customized 3D-printed composite resin veneer restorations fabricated using digital design and additive manufacturing technology and bonded according to the manufacturer's recommended adhesive protocol
Eligibility Criteria
You may qualify if:
- Good oral hygiene and satisfactory periodontal health
- Patients requiring esthetic rehabilitation of anterior teeth
- Presence of enough enamel for bonding
You may not qualify if:
- Non-vital teeth or teeth requiring endodontic treatment
- Severe malocclusion or parafunctional habits (e.g., bruxism or clenching)
- Patients with severe intrinsic discoloration requiring alternative treatment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Tanta Universitylead
Study Sites (1)
Restorative Department, Faculty of Dentistry, Tanta University
Tanta, Tanta, 31527, Egypt
Related Publications (5)
Mandurino M, Cortili S, Coccoluto L, Greco K, Cantatore G, Gherlone EF, Vichi A, Paolone G. Mechanical Properties of 3D Printed vs. Subtractively Manufactured Composite Resins for Permanent Restorations: A Systematic Review. Materials (Basel). 2025 Feb 24;18(5):985. doi: 10.3390/ma18050985.
PMID: 40077210BACKGROUNDVeerapeindee P, Rungsiyakull P, Jia-Mahasap W. Wear resistance of 3D printed, milled, and prefabricated methacrylate-based resin materials: An in vitro study. J Prosthet Dent. 2025 Mar;133(3):904.e1-904.e8. doi: 10.1016/j.prosdent.2024.12.006. Epub 2024 Dec 20.
PMID: 39709262RESULTBalestra D, Lowther M, Goracci C, Mandurino M, Cortili S, Paolone G, Louca C, Vichi A. 3D Printed Materials for Permanent Restorations in Indirect Restorative and Prosthetic Dentistry: A Critical Review of the Literature. Materials (Basel). 2024 Mar 18;17(6):1380. doi: 10.3390/ma17061380.
PMID: 38541534RESULTAlghauli MA, Alqutaibi AY. 3D-printed intracoronal restorations, occlusal and laminate veneers: Clinical relevance, properties, and behavior compared to milled restorations; a systematic review and meta-analysis. J Esthet Restor Dent. 2024 Aug;36(8):1153-1170. doi: 10.1111/jerd.13228. Epub 2024 Mar 29.
PMID: 38551205RESULTDaghrery A. Color Stability, Gloss Retention, and Surface Roughness of 3D-Printed versus Indirect Prefabricated Veneers. J Funct Biomater. 2023 Sep 28;14(10):492. doi: 10.3390/jfb14100492.
PMID: 37888157RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Masking Details
- Double (Participant, Outcomes Assessor)
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
July 2, 2026
First Posted
July 9, 2026
Study Start
April 25, 2025
Primary Completion (Estimated)
April 26, 2027
Study Completion (Estimated)
April 29, 2027
Last Updated
July 9, 2026
Record last verified: 2026-07
Data Sharing
- IPD Sharing
- Will not share