Children Acceptance of AgNP Mouthwash Against Chlorhexidine Mouthwash
Comparative Assessment of Children's Acceptance and Compliance of Mouthwash Containing Silver Nanoparticles Compared to Chlorhexidine Mouthwash: A Randomized Clinical Trial.
1 other identifier
interventional
60
0 countries
N/A
Brief Summary
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2026
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 9, 2025
CompletedFirst Posted
Study publicly available on registry
September 30, 2025
CompletedStudy Start
First participant enrolled
January 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2026
ExpectedSeptember 30, 2025
June 1, 2025
2 months
September 9, 2025
September 28, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
children acceptance and compliance
it will be measured by likert scale (1-5) 1 (strongly disagree) 5 (strongly agree)
15 days
Secondary Outcomes (3)
Gingival health
15 days
plaque thickness at gingival margin
15 days
color stability of composite restoration of anterior teeth
15 days
Study Arms (3)
use AgNP mouthwash as experimental group
EXPERIMENTALnano cure mouthwash
use hexitol mouthwash (CHX) as experimental group
EXPERIMENTALorovex mouthwash (CHX) as a comparator group
ACTIVE COMPARATORInterventions
nano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients
the concentration of chlorhexidine
chlorhexidine mouthwash 0.2% (orovex )
Eligibility Criteria
You may qualify if:
- Children aged from 6 to 12 in good general health and medically free
- Cooperative patient who will care about attending the follow-up visit
- Acceptance of the parents to sign the informed consent
You may not qualify if:
- Children who are unable to attend the follow-up visit
- Medically compromised patient
- Handi-capped patient
- Parents refuse to sign informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Master's student (Dentist)
Study Record Dates
First Submitted
September 9, 2025
First Posted
September 30, 2025
Study Start
January 1, 2026
Primary Completion
March 1, 2026
Study Completion (Estimated)
June 1, 2026
Last Updated
September 30, 2025
Record last verified: 2025-06
Data Sharing
- IPD Sharing
- Will not share
cause it a private data and it's mentioned in the informed consent that the data of the participants will be private and not published