Brief Summary

To compare postprandial plasma amino acid availability, expressed as incremental area under the curve (iAUC), over a 6 hour period following ingestion of 25 g of different protein isolates in healthy, young adults. The primary objective is divided into the following 2 sub-studies, each with 3 comparisons:

Sub-study 1: whey protein, calcium caseinate, sodium caseinate.
Sub-study 2: calcium caseinate, magnesium caseinate, potassium caseinate.

Trial Health

Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

participants targeted

Target at below P25 for not_applicable

Timeline

10mo left

Started Sep 2026

Shorter than P25 for not_applicable

Geographic Reach

1 country

1 active site

Status

not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

10 months study duration

First Submitted

Initial submission to the registry

June 24, 2026

Completed

6 days until next milestone

First Posted

Study publicly available on registry

June 30, 2026

Completed

3 months until next milestone

Study Start

First participant enrolled

September 15, 2026

Expected

10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2027

Last Updated

June 30, 2026

Status Verified

June 1, 2026

Enrollment Period

10 months

First QC Date

June 24, 2026

Last Update Submit

June 24, 2026

Conditions

Protein Metabolism

Keywords

Amino acidSatiety hormoneMineralsProtein kinetics

Outcome Measures

Primary Outcomes (1)

Six-hour postprandial plasma total amino acid availability following ingestion of 25 grams of different protein isolates in healthy, young adults
Plasma total amino acid availability is expressed as the incremental area under the curve (iAUC) and compared between whey protein, calcium caseinate and sodium caseinate (sub-study 1) and between calcium caseinate, magnesium caseinate and potassium caseinate (sub-study 2).
Six hours

Secondary Outcomes (5)

Plasma essential amino acid concentrations
Essential amino acid concentrations are derived from blood samples taken before beverage ingestion and during the six-hour postprandial time-period (at 15, 30, 45, 60, 75, 90, 120, 150, 180, 210, 240, 300 and 360 minutes following beverage ingestion).
Non-essential amino acid concentrations
Nonssential amino acid concentrations are derived from blood samples taken before beverage ingestion and during the six-hour postprandial time-period (at 15, 30, 45, 60, 75, 90, 120, 150, 180, 210, 240, 300 and 360 minutes following beverage ingestion).
Plasma amino acid kinetics
During the six-hour postprandial period
Circulating mineral concentrations
During the six-hour postprandial period
Glucagon-like peptide-1 concentrations
During the six-hour postprandial period