Comparing Digital and Collaborative Gamified Reinforcement Strategies for HPV Literacy and Retention Among Nursing Students

NCT07667127 | Not Yet Recruiting

• 1 other identifier: 2026-HPV Literacy
• Study Type: interventional
• Target: 64
• Locations: 0 countries
• Sites: N/A

Brief Summary

This randomized comparative study aims to evaluate the effectiveness of two gamified reinforcement strategies, Gimkit and Escape Room, on human papillomavirus (HPV) literacy, short-term retention, and gameful learning experiences among undergraduate nursing students. Following standardized theoretical instruction on HPV infection, participants will be randomly assigned to either a digital quiz-based gamification intervention (Gimkit) or a collaborative Escape Room activity. Outcomes will be assessed using the Human Papillomavirus Literacy Scale (HPV-LS) and the Gameful Experience Scale (GAMEX) at multiple time points, including baseline, post-theoretical instruction, post-intervention, and one-month follow-up.

Conditions

Health Literacy; Human Papillomavirus (HPV) Infection; Nursing Education

Keywords

HPV literacy; nursing education; educational intervention; gimkit; escape room; Human Papillomavirus; game-based learning; gamification; knowledge retention

Outcome Measures

Primary Outcomes (1)

• Human Papillomavirus Literacy

  HPV literacy will be measured using the Human Papillomavirus Literacy Scale (HPV-LS). Scores range from 24 to 120; higher scores indicate higher literacy. Higher scores indicate higher levels of HPV literacy.

  Baseline (Day 0, 21.09.2026), immediately after theoretical education (Day 0), immediately after the intervention (Day 7, 28.09.2026), and follow-up (Day 28, 26.10.2026)

Secondary Outcomes (1)

• Gamified Learning Experience

  Day 7 (28.09.2026)

Study Arms (2)

Escape Room Group

EXPERIMENTAL

Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participants will engage in a collaborative Escape Room activity involving HPV-related problem-solving tasks, crossword puzzles, matching exercises, and educational challenges completed in small groups.

Behavioral: Escape Room-Based Gamified Reinforcement

Gimkit Group

EXPERIMENTAL

Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by a digital quiz-based educational reinforcement activity (Gimkit) designed according to retrieval practice and test-enhanced learning principles to improve HPV literacy and knowledge retention. Participants will complete an individual digital gamification activity using the Gimkit platform. The intervention includes multiple-choice and true/false questions focusing on HPV transmission, vaccination, screening, prevention, and nursing responsibilities. Immediate feedback will be provided throughout the activity.

Behavioral: Gimkit-Based Gamified Reinforcement

Interventions

Gimkit-Based Gamified Reinforcement BEHAVIORAL

Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions designed to reinforce HPV-related knowledge.The Gimkit intervention will consist of a digitally structured, quiz-based gamification activity including multiple-choice and true/false questions related to HPV infection, vaccination, screening, and prevention. The activity will design to support retrieval practice and immediate feedback processes. Students individually will access the game using smartphones and personal login codes in the classroom environment. All participants will start the activity simultaneously and completed the questions within 20 minutes while using headphones to minimize distraction and interaction among students.

Gimkit Group

Escape Room-Based Gamified Reinforcement BEHAVIORAL

A collaborative educational reinforcement activity designed according to constructivist and experiential learning principles to improve HPV literacy and knowledge retention. Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room intervention will design as a collaborative, problem-solving-based learning activity conducted in groups of 7 students. Participants will randomly assigned to 4 groups and placed in separate classrooms to prevent interaction between groups. The escape room will consist of 4 stations involving HPV-related crossword puzzles, word-search activities, matching exercises, and problem-solving tasks developed according to the study learning objectives. Students will attempt to complete all activities within 20 minutes under moderator supervision. Groups can request hints from the moderator when needed; however, each hint resulted in a 1-minute time penalty.

Escape Room Group

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Being a nursing student
• Voluntary participation
• Aged 18 years or older
• Participation in all measurement points
• Ownership of a smartphone
• Internet access
• Having headphones

You may not qualify if:

• Incomplete data forms
• Not participating in intervention sessions
• Absence in posttest or follow-up

Sponsors & Collaborators

• Aydin Adnan Menderes University: lead

MeSH Terms

Conditions

Papillomavirus Infections; Infections

Condition Hierarchy (Ancestors)

Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Communicable Diseases; DNA Virus Infections; Virus Diseases; Tumor Virus Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

NİHAL TAŞKIRAN

CONTACT

+905055729899; nihaltaskiran@adu.edu.tr

Abdülkadir Deniz

CONTACT

+905323019812; kadirdeniz0973@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Aydın Adnan Menderes University Nursing Faculty

Model Details: Participants will be randomly assigned to one of two educational reinforcement interventions following standardized HPV theoretical instruction. One group will receive a digital quiz-based gamification intervention using Gimkit, whereas the second group will participate in a collaborative Escape Room activity. Outcome measures will be assessed longitudinally across four measurement points.

Study Record Dates

• First Submitted: June 19, 2026
• First Posted: June 24, 2026
• Study Start (Estimated): September 21, 2026
• Primary Completion (Estimated): October 26, 2026
• Study Completion (Estimated): October 26, 2026
• Last Updated: July 2, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share