NCT07642011

Brief Summary

This study will be conducted to investigate the relationship between knee joint pain intensity and joint position sense accuracy in patients with patellofemoral pain syndrome (PFPS) in a single-leg squat position.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for all trials

Timeline
5mo left

Started Jul 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 6, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 11, 2026

Completed
20 days until next milestone

Study Start

First participant enrolled

July 1, 2026

Expected
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2026

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 20, 2026

Last Updated

June 11, 2026

Status Verified

June 1, 2026

Enrollment Period

5 months

First QC Date

June 6, 2026

Last Update Submit

June 6, 2026

Conditions

Keywords

Knee PainProprioceptionSingle Leg SquatPatellofemoral Pain Syndrome

Outcome Measures

Primary Outcomes (3)

  • pain intensity

    nemerial pain rating scale will be used to assess pain intensity. It comprises of 11 point ''horizontal scale'' of 0-10 in Arabic numerals anchored by the two ends, the left (0 indicating no pain at all) and right (10 indicating the worst ).

    up to one day

  • knee disability

    The Arabic version of the Kujala patellofemoral pain scoring system is a questionnaire to assess the patient with PFP. It includes 13 points based on the following factors: presence of a limp, need for support, walking ability, stair climbing, squatting, running, jumping, prolonged sitting with knees flexed, pain, swelling, abnormal painful kneecap movement, atrophy of the thigh, and flexion deficiency. Each question has multiple answers with points reflecting the severity of symptoms and level of functional limitation. Each question is assigned a score of either up to 5 or 10, and the total score for the Kujala questionnaire is 100. The higher the score, the better the function

    up to one day

  • knee joint position error (knee joint proprioception)

    Digital-goniometer will be used to assess joint position error.the digital-goniometer will be attached to the knee joint in the neutral knee position. The fixed arm will be placed in parallel to an imaginary line between the head of the fibula and the lateral malleolus. The movable arm will be placed in parallel to an imaginary line between the greater trochanter and the lateral condyle of the femur. The digital-goniometer will be zeroed when the subject is standing motionless in the anatomic position. To prevent slippage during knee joint motion, the end blocks will be adhered to the tested leg with double-sided adhesive tape and further secured in place with adhesive tape. Digital-goniometer readings records knee joint angular displacements relative to zero

    up to one day

Study Arms (1)

patellofemoral pain syndrome patients

Eighty-two patellofemoral pain syndrome patients will be included in this group. their ages range from 18 to 35 years old, with body mass index 18-25 kg/cm2

Other: patellofemoral pain syndrome patients

Interventions

eighty two patellofemoral pain syndrome had Positive eccentric step test,Anterior or retropatellar knee pain present during at least two of the following - ascending/descending stairs, hopping/running, squatting, kneeling and prolonged sitting and Pain on palpation of patellar facets. their ages between 18-35 years old.

patellofemoral pain syndrome patients

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

eighty two patellofemoral pain syndrome had Positive eccentric step test,Anterior or retropatellar knee pain present during at least two of the following - ascending/descending stairs, hopping/running, squatting, kneeling and prolonged sitting and Pain on palpation of patellar facets. their ages between 18-35 years old.

You may qualify if:

  • Age ranges from 18-35 years
  • BMI ranges from 18-25 kg/m2
  • Positive eccentric step test
  • Anterior or retropatellar knee pain present during at least two of the following - ascending/descending stairs, hopping/running, squatting, kneeling and prolonged sitting
  • Pain on palpation of patellar facets
  • Insidious onset of symptoms vague and non-localized pain at anterior of knee for at least three months ( unrelated to a traumatic incident.

You may not qualify if:

  • Knee pain is more than 6 score on ANPRS.
  • History of traumatic patellar dislocation or subluxation
  • Osteoarthritis in the knee, ankle or hip joints, injury of cruciate ligaments or menisci
  • Previous orthopedic disorders or neurologic deficit of the lower limbs, any sensory problems, leg length discrepancy, neuromuscular disease like multiple sclerosis
  • Athletic patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Central Study Contacts

esraa el-sayed, master

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator : esraa adel el-sayed

Study Record Dates

First Submitted

June 6, 2026

First Posted

June 11, 2026

Study Start (Estimated)

July 1, 2026

Primary Completion (Estimated)

November 20, 2026

Study Completion (Estimated)

November 20, 2026

Last Updated

June 11, 2026

Record last verified: 2026-06