Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period

NCT07604948 | Recruiting

• 1 other identifier: GZSU-IPC-BB-2024
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period. Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group. Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions. Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.

Conditions

Lower Extremity Explosive Power Deficit; Sports Recovery; Basketball Performance; Muscle Fatigue

Keywords

Ischemic preconditioning; Basketball; Lower extremity explosiveness; Physical recovery; Post-match recovery

Outcome Measures

Primary Outcomes (6)

• Squat Jump (SJ) height

  Change from baseline in lower extremity concentric explosive power measured by Smart Jump portable contact mat (cm).

  Baseline (Week 0) and Post-intervention (Week 8)

• Countermovement Jump (CMJ) height

  Change from baseline in lower extremity reactive explosive power without arm swing (cm).

  Baseline and Week 8

• Reactive Strength Index (RSI)

  Change from baseline in RSI derived from 30cm drop jump using Smart Jump system (m/s).

  Baseline and Week 8

• Standing Long Jump

  Change from baseline in lower extremity horizontal explosive power (cm).

  Baseline and Week 8

• T-Test (T-run)

  Change from baseline in multi-directional agility performance (seconds).

  Baseline and Week 8

• 3/4 Court Sprint

  Change from baseline in linear sprint speed over 3/4 basketball court distance (\~21m, seconds).

  Baseline and Week 8

Secondary Outcomes (4)

• Blood Lactate Accumulation

  Baseline and Week 8

• Peak Power (10s Test)

  Baseline and Week 8

• Mean Power (10s Test)

  Baseline and Week 8

• Testosterone/Cortisol Ratio

  Baseline and Week 8

Study Arms (2)

IPC Group

EXPERIMENTAL

Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475). Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions. The intervention was conducted twice per week for 6 weeks. Cuff placement: at the inguinal crease of the thigh. Subject position: supine, alternating between left and right legs.

Device: Ischemic Preconditioning

Sham Control Group

ACTIVE COMPARATOR

Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training. Twice weekly for 6 weeks.

Device: Placebo Ischemic Preconditioning

Interventions

Ischemic Preconditioning DEVICE

Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475). Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions. The intervention was conducted twice per week for 6 weeks. Cuff placement: at the inguinal crease of the thigh. Subject position: supine, alternating between left and right legs.

IPC Group

Placebo Ischemic Preconditioning DEVICE

Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training. Twice weekly for 6 weeks.

Sham Control Group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male basketball students at Guangzhou Sport University.
• Regular participants in basketball training/practice.
• Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
• Blood pressure within normal range.
• No history of lower extremity musculoskeletal injury within the past 6 months.
• Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
• Voluntary participation with signed informed consent.

You may not qualify if:

• Presence of acute or chronic diseases affecting exercise performance.
• History of deep vein thrombosis or coagulation disorders.
• Presence of skin lesions or infections at the thigh cuff placement site.
• Participation in other concurrent lower extremity strength/power training programs outside the study.
• Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
• Inability to complete the full 6-week intervention and testing protocol.

Sponsors & Collaborators

• Guangzhou Sport University: lead

Study Sites (1)

Guangzhou Sport University

Guangzhou, Guangdong, 510430, China

RECRUITING

Related Publications (7)

• Ou Z, Yang L, Zhu H, Weng X, Xu G. Ischemic preconditioning enhances autonomic nervous system modulation during frequency speed of kick test in taekwondo athletes: a randomized crossover study. BMC Sports Sci Med Rehabil. 2026 Feb 12;18(1):136. doi: 10.1186/s13102-026-01602-2.

  PMID: 41680854 BACKGROUND

• Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. doi: 10.1249/MSS.0b013e318206845d.

  PMID: 21131871 BACKGROUND

• Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653.

  PMID: 34682399 BACKGROUND

• Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25.

  PMID: 35400298 BACKGROUND

• Carvalho L, Barroso R. Ischemic Preconditioning Improves Strength Endurance Performance. J Strength Cond Res. 2019 Dec;33(12):3332-3337. doi: 10.1519/JSC.0000000000002846.

  PMID: 30844989 BACKGROUND

• Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.

  PMID: 31333890 BACKGROUND

• Bailey TG, Jones H, Gregson W, Atkinson G, Cable NT, Thijssen DH. Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sports Exerc. 2012 Nov;44(11):2084-9. doi: 10.1249/MSS.0b013e318262cb17.

  PMID: 22843115 BACKGROUND

MeSH Terms

Interventions

Ischemic Preconditioning

Intervention Hierarchy (Ancestors)

Therapeutics; Investigative Techniques

Central Study Contacts

Ziyue Ou, PHD

CONTACT

+8615626121623; 105852022100090@stu.gzsport.edu.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 17, 2026
• First Posted: May 22, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): July 15, 2026
• Study Completion (Estimated): July 15, 2026
• Last Updated: May 22, 2026

Record last verified: 2026-05

Locations

CN (1)