Verbal Intent and Gaze Cues on Action Prediction in ASD

NCT07597694 | Completed

• 1 other identifier: UESTC-GazeLab-04
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded.

Conditions

Autism Spectrum Disorder (ASD); Intellectual Disability

Keywords

Joint Attention; Action Prediction; eye tracking

Outcome Measures

Primary Outcomes (2)

• Percentage of Total Fixation Duration on Objects

  Percentage of Total Fixation Duration on Objects = (Total time fixating on target objects ÷ Total fixation duration across the scene) × 100%. It measures how much of overall viewing time is spent attending to predefined objects, reflecting attentional priority and object-driven cognitive engagement, normalized for individual differences.

  During the full 13 seconds video presentation

• The time to first fixation on an object within each defined TOI (Time of Interest)

  Time to First Fixation on an Object within a TOI = time elapsed from TOI onset until the first fixation lands on that object. It measures how quickly attention is drawn to a target, reflecting salience or search efficiency. Shorter times indicate faster capture.

  During the 0-2 s, 2-6 s, and 6-8 s intervals of video

Study Arms (3)

Autism Spectrum Disorder (ASD) Group

Typically Developing (TD) Group

Intellectual Disability（ID）Group

Eligibility Criteria

• Age: 3 Years - 10 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

A total of 80 children (aged 3-10 years) were initially recruited and divided into three groups: 29 typically developing (TD) children (25 boys, 4 girls) from a kindergarten or primary school in Sichuan Province; 26 children with autism spectrum disorder (ASD) (20 boys, 6 girls) from a local disability federation or autism rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed and assessed with the Autism Diagnostic Observation Schedule (ADOS); and 25 children with intellectual disability (ID) (14 boys, 11 girls) from a disability federation or rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed. Based on eye-tracking data, 4 ASD participants and 1 ID participant whose total fixation duration accounted for less than 50% of the total trial time were excluded. Consequently, the final sample included 29 TD children (25 boys, 4 girls), 22 ASD children (18 boys, 4 girls), and 24 ID children (13 boys, 11 girls) for data analysis.

You may qualify if:

• \- Children clinically diagnosed with Autism Spectrum Disorder (ASD). Typically developing (TD) children with no developmental or neurological disorders.
• Children clinically diagnosed with Intellectual Disability (ID).
• Common criteria for all groups: Normal or corrected-to-normal vision, no color vision deficiencies, normal hearing, and written informed consent provided by their legal guardians.

You may not qualify if:

• \- Failure to meet the study's group-specific screening cutoffs on the Social Responsiveness Scale (SRS) and Social Communication Questionnaire (SCQ).
• Failure to meet the study's group-specific screening cutoffs on the Autism Diagnostic Observation Schedule (ADOS).
• Known genetic syndromes, significant hearing loss, or uncorrectable visual impairment.

Sponsors & Collaborators

• University of Electronic Science and Technology of China: lead

Study Sites (1)

School of Foreign Languages, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

Location

MeSH Terms

Conditions

Autism Spectrum Disorder; Intellectual Disability

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 6, 2026
• First Posted: May 19, 2026
• Study Start: December 15, 2025
• Primary Completion: January 29, 2026
• Study Completion: March 27, 2026
• Last Updated: May 19, 2026

Record last verified: 2026-05

Locations

CN (1)