Emotion Intensity Modulates Intention in ASD

NCT07597655 | Completed

• 1 other identifier: UESTC-GazeLab-06
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study used eye-tracking to examine how emotional expression intensity (low/medium/high) influences intention understanding in children with ASD, PDD, and TD during a puzzle-search task.

Conditions

Autism Spectrum Disorder (ASD); Intellectual Disability

Keywords

emotional expression intensity; eye tracking; hidden Markov modeling (HMM); social cognition

Outcome Measures

Primary Outcomes (3)

• The visitation rate of the AOI

  Number of times the gaze enters the AOI per unit time. It measures how frequently the AOI is re-visited. Higher rates indicate repeated returns, reflecting high interest or difficulty disengaging; lower rates suggest rare or brief attention.

  From second 3 to second 30 of the experimental stimulus.

• The proportions of fixation duration

  fixation duration on an AOI ÷ total fixation duration (or across multiple AOIs). It measures the relative amount of attention allocated to a specific area. Higher proportions indicate prioritized or deeper processing of that region.

  During the full 40 seconds video presentation.

• The first fixation latency

  The First Fixation Latency = time from TOI onset until the first fixation lands on a predefined object. It measures how fast attention is initially drawn to that object. Shorter latencies indicate higher salience or more efficient search.

  During the full 40 seconds video presentation.

Secondary Outcomes (1)

• The face fixation transition ratio

  From second 13 to second 15 of the experimental stimulus.

Study Arms (3)

Autism Spectrum Disorder (ASD) Group

Typically Developing (TD) Group

Intellectual Disability（ID）Group

Eligibility Criteria

• Age: 3 Years - 10 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Failure to meet the study's group-specific screen cutoffs on the Social Responsiveness Scale(SRS) and ADOS-2; Known genetic syndromes, significant hearing loss, or uncorrectable visual impairment.

You may qualify if:

• \- Typically developing children without any developmental or neurological disorders.
• Confirmed clinical diagnosis of Autism Spectrum Disorder and reconfirmed by the criteria of the Diagnostic Observation Table for ASD, Second Edition (ADOS-2).
• Confirmed clinical diagnosis of Intellectual Disability and the ADOS-2 with a comparison score below the ASD diagnostic cut-off score (comparison score≤2).

You may not qualify if:

• \- Normal or corrected-to-normal vision, no color vision deficiencies, and legal guardian provided written informed consent.

Sponsors & Collaborators

• University of Electronic Science and Technology of China: lead

Study Sites (1)

School of Foreign Languages, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

Location

MeSH Terms

Conditions

Autism Spectrum Disorder; Intellectual Disability

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 6, 2026
• First Posted: May 19, 2026
• Study Start: December 15, 2025
• Primary Completion: January 29, 2026
• Study Completion: March 27, 2026
• Last Updated: May 19, 2026

Record last verified: 2026-05

Locations

CN (1)