NCT07597265

Brief Summary

This study examined the acute effects of caffeinated chewing gum on volleyball performance in trained female volleyball players. Caffeine is commonly used by athletes to improve performance, but less is known about whether caffeinated gum is useful during volleyball-specific activity. Participants completed three testing sessions in a randomized crossover design. In one session, they chewed placebo gum. In another session, they chewed caffeinated gum containing a single 300 mg dose of caffeine. In the third session, they received the same total amount of caffeine as three separate 100 mg doses given at 30-minute intervals. The study assessed volleyball-specific skill performance, including attack, block, and defense efficiency, during a volleyball-specific skill game. Vertical jump height, heart rate, perceived exertion, side effects, and condition guessing were also recorded.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 5, 2025

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 23, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 23, 2026

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

May 11, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 19, 2026

Completed
Last Updated

May 19, 2026

Status Verified

May 1, 2026

Enrollment Period

9 months

First QC Date

May 11, 2026

Last Update Submit

May 15, 2026

Conditions

Keywords

CaffeineCaffeinated gumVolleyballAthletic performanceVertical jump

Outcome Measures

Primary Outcomes (3)

  • Attack efficiency

    Attack efficiency was assessed during a 30-minute volleyball-specific skill game using video recordings and Data Volley software. Values were expressed as percentages.

    During the 30-minute volleyball-specific skill game in each experimental trial

  • Block efficiency

    Block efficiency was assessed during a 30-minute volleyball-specific skill game using video recordings and Data Volley software. Values were expressed as percentages.

    During the 30-minute volleyball-specific skill game in each experimental trial

  • Defense efficiency

    Defense efficiency was assessed during a 30-minute volleyball-specific skill game using video recordings and Data Volley software. Values were expressed as percentages.

    During the 30-minute volleyball-specific skill game in each experimental trial

Secondary Outcomes (3)

  • Change in vertical jump height

    From immediately before to immediately after each experimental trial

  • Heart rate

    Continuously during each experimental trial

  • Change in rating of perceived exertion

    From immediately before to immediately after each experimental trial

Other Outcomes (1)

  • Side effects

    Immediately after each experimental trial

Study Arms (6)

Placebo, Single-Dose Caffeine, Partial-Dose Caffeine Arm Type: Experimental

EXPERIMENTAL

Participants received placebo gum in the first session, single-dose caffeinated gum in the second session, and partial-dose caffeinated gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Placebo, Partial-Dose Caffeine, Single-Dose Caffeine

EXPERIMENTAL

Participants received placebo gum in the first session, partial-dose caffeinated gum in the second session, and single-dose caffeinated gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Single-Dose Caffeine, Placebo, Partial-Dose Caffeine

EXPERIMENTAL

Participants received single-dose caffeinated gum in the first session, placebo gum in the second session, and partial-dose caffeinated gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Single-Dose Caffeine, Partial-Dose Caffeine, Placebo

EXPERIMENTAL

Participants received single-dose caffeinated gum in the first session, partial-dose caffeinated gum in the second session, and placebo gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Partial-Dose Caffeine, Placebo, Single-Dose Caffeine

EXPERIMENTAL

Participants received partial-dose caffeinated gum in the first session, placebo gum in the second session, and single-dose caffeinated gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Partial-Dose Caffeine, Single-Dose Caffeine, Placebo

EXPERIMENTAL

Participants received partial-dose caffeinated gum in the first session, single-dose caffeinated gum in the second session, and placebo gum in the third session. Sessions were separated by one week.

Dietary Supplement: Single-dose caffeinated gumDietary Supplement: Partial-dose caffeinated gumDietary Supplement: Placebo gum

Interventions

Single-dose caffeinated gumDIETARY_SUPPLEMENT

Participants chewed three pieces of caffeinated gum containing 100 mg caffeine per piece, providing a total dose of 300 mg caffeine. The gum was chewed for 5 minutes and then discarded.

Also known as: Caffeine gum, Caffeinated chewing gum
Partial-Dose Caffeine, Placebo, Single-Dose CaffeinePartial-Dose Caffeine, Single-Dose Caffeine, PlaceboPlacebo, Partial-Dose Caffeine, Single-Dose CaffeinePlacebo, Single-Dose Caffeine, Partial-Dose Caffeine Arm Type: ExperimentalSingle-Dose Caffeine, Partial-Dose Caffeine, PlaceboSingle-Dose Caffeine, Placebo, Partial-Dose Caffeine

Participants received three separate pieces of caffeinated gum containing 100 mg caffeine per piece. One piece was chewed for 5 minutes at each administration time point, with doses given at 30-minute intervals, providing a total dose of 300 mg caffeine.

Also known as: Caffeine gum, Caffeinated chewing gum
Partial-Dose Caffeine, Placebo, Single-Dose CaffeinePartial-Dose Caffeine, Single-Dose Caffeine, PlaceboPlacebo, Partial-Dose Caffeine, Single-Dose CaffeinePlacebo, Single-Dose Caffeine, Partial-Dose Caffeine Arm Type: ExperimentalSingle-Dose Caffeine, Partial-Dose Caffeine, PlaceboSingle-Dose Caffeine, Placebo, Partial-Dose Caffeine
Placebo gumDIETARY_SUPPLEMENT

Participants chewed caffeine-free placebo gum for 5 minutes. The placebo gum was selected to be similar in shape and color to the caffeinated gum.

Also known as: Caffeine-free gum, Placebo chewing gum
Partial-Dose Caffeine, Placebo, Single-Dose CaffeinePartial-Dose Caffeine, Single-Dose Caffeine, PlaceboPlacebo, Partial-Dose Caffeine, Single-Dose CaffeinePlacebo, Single-Dose Caffeine, Partial-Dose Caffeine Arm Type: ExperimentalSingle-Dose Caffeine, Partial-Dose Caffeine, PlaceboSingle-Dose Caffeine, Placebo, Partial-Dose Caffeine

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female volleyball players aged 18 to 35 years.
  • Apparently healthy.
  • Daily caffeine intake ≤300 mg.
  • Minimum of 5 years of regular volleyball training experience.
  • Training for at least 120 minutes at least 3 days per week.
  • Competing in national or international volleyball matches.
  • Provided written informed consent before participation.

You may not qualify if:

  • Serious injury or trauma within the past 6 months that could affect volleyball performance.
  • Illness or inability to continue the study protocol during the research period.
  • Development of side effects during caffeinated gum administration that prevented continuation.
  • Regular alcohol or drug use that could affect the study outcomes.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ege University, Faculty of Sport Sciences

Izmir, Bornova, 35040, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 11, 2026

First Posted

May 19, 2026

Study Start

August 5, 2025

Primary Completion

April 23, 2026

Study Completion

April 23, 2026

Last Updated

May 19, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because the dataset contains participant-level performance and physiological data from a small group of elite female volleyball players, which may increase the risk of participant identification.

Locations