NCT07546851

Brief Summary

This study examined the interaction between rotational foot positioning during leg press and individuals' habitual foot progression angle (FPA) phenotype on the acute contractile response of the vastus medialis muscle

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2026

Completed
17 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 18, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 5, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

April 7, 2026

Completed
16 days until next milestone

First Posted

Study publicly available on registry

April 23, 2026

Completed
Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

17 days

First QC Date

April 7, 2026

Last Update Submit

April 20, 2026

Conditions

Keywords

Foot progression angleLeg pressTensiomyographyVastus medialisMuscle contractile propertiesResistance training

Outcome Measures

Primary Outcomes (2)

  • Change in Maximal Radial Deformation (Dm) of Vastus Medialis

    Dm reflects the maximal radial displacement of the muscle belly in response to electrical stimulation, assessed via tensiomyography (TMG). Pre-to-post exercise change in Dm was compared between congruent and incongruent foot rotation conditions.

    Immediately before and within 90 seconds after completion of the exercise protocol

  • Change in Contraction Time (Tc) of Vastus Medialis

    Tc reflects the time required for the muscle to contract from 10% to 90% of maximal radial displacement, assessed via tensiomyography (TMG). Pre-to-post exercise change in Tc was compared between congruent and incongruent foot rotation conditions.

    Immediately before and within 90 seconds after completion of the exercise protocol

Secondary Outcomes (1)

  • Change in Delay Time (Td) of Vastus Medialis

    Immediately before and within 90 seconds after completion of the exercise protocol

Study Arms (2)

Congruent Foot Position

EXPERIMENTAL

Participants performed leg press exercise with a foot rotation position congruent with their habitual foot progression angle phenotype. For HFPA group: 30° toe-out; for NFPA group: 0° neutral.

Behavioral: Congruent Foot Position Leg Press

Incongruent Foot Position

EXPERIMENTAL

Participants performed leg press exercise with a foot rotation position incongruent with their habitual foot progression angle phenotype. For HFPA group: 0° neutral; for NFPA group: 30° toe-out.

Behavioral: Incongruent Foot Position Leg Press

Interventions

Leg press exercise performed with foot rotation position congruent with the participant's habitual foot progression angle phenotype. HFPA group: 30° toe-out; NFPA group: 0° neutral. Protocol: 2×15 repetitions at 40% 1RM followed by 4×10 repetitions at 75-80% 1RM.

Congruent Foot Position

Leg press exercise performed with foot rotation position incongruent with the participant's habitual foot progression angle phenotype. HFPA group: 0° neutral; NFPA group: 30° toe-out. Protocol: 2×15 repetitions at 40% 1RM followed by 4×10 repetitions at 75-80% 1RM.

Incongruent Foot Position

Eligibility Criteria

Age20 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 20 and 35 years
  • Minimum five years of regular resistance training experience
  • Currently active in training
  • Foot progression angle measurements of both feet meeting the defined threshold values for group classification

You may not qualify if:

  • History of lower extremity surgery or serious musculoskeletal injury within the past one year
  • Congenital or acquired foot deformity
  • History of neurological, cardiovascular, or metabolic disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Giresun University - Sports Science Faculty

Giresun, Centre, 28100, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Masking Details
The investigator performing TMG measurements was blinded to participants' phenotype group and exercise condition (single-blind).
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Each participant performed leg press exercise under both congruent and incongruent foot rotation conditions in a crossover design, with a 48-hour washout period between sessions.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 7, 2026

First Posted

April 23, 2026

Study Start

January 1, 2026

Primary Completion

January 18, 2026

Study Completion

April 5, 2026

Last Updated

April 23, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared due to ethical restrictions and participant confidentiality agreements.

Locations