Resistance Exercise and Sleep Quality by Chronotype

NCT07234812 | Not Yet Recruiting

• 1 other identifier: E-10840098-202.3.02-1592
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults. Participants with different daily activity patterns (morning or evening types) will take part in an 8-week online exercise program. The study will compare how exercise affects sleep, mood, and daily rhythm across these groups.

Conditions

Physical Therapy; Resistance Exercise; Sleep Disturbances; Sleep Quality; Chronotype; Circadian Rhythm; Health Behavior / Well-Being

Keywords

sleep disturbance; Sleep quality; Chronotype; Morningness-eveningness; Circadian rhythm; Resistance exercise; Home-based exercise; Sleep and exercise; Physical activity and sleep; Physical Therapy; Exercise; Telerehabilitation; Munich Chronotype Questionnaire (MCTQ); Pittsburgh Sleep Quality Index (PSQI); Mood (BRUMS, DASS-21); Randomized controlled trial; Physical therapy and rehabilitation

Outcome Measures

Primary Outcomes (1)

• Change in Sleep Quality Assessed by Pittsburgh Sleep Quality Index (PSQI)

  Sleep quality will be measured using the Pittsburgh Sleep Quality Index (PSQI), a validated 19-item self-report questionnaire that evaluates sleep patterns over the past month. The PSQI generates seven component scores (subjective sleep quality, latency, duration, efficiency, disturbances, use of medication, daytime dysfunction), which are summed into a global score ranging from 0 to 21, with higher scores indicating poorer sleep quality. Assessments will be conducted at baseline (week 0), midpoint (week 4), and end of study (week 8). The primary endpoint is the change in global PSQI score from baseline to week 8, comparing differences between morning and evening chronotype groups following the resistance exercise program.

  Baseline, Week 4, and Week 8; primary comparison is change from baseline to Week 8

Secondary Outcomes (7)

• Change in Circadian Alignment Assessed by Munich Chronotype Questionnaire (MCTQ)

  Baseline and Week 8

• Change in Mood Assessed by Brunel Mood Scale (BRUMS)

  Baseline, Week 4, and Week 8

• Perceived Effort Assessed by OMNI Perceived Exertion Scale for Resistance Exercise (OMNI-RES)

  Throughout Weeks 1-8

• Muscle Soreness Assessed by 7-Point Likert Scale

  After each exercise session, Weeks 1-8

• Change in Physical Activity Level Assessed by International Physical Activity Questionnaire-Short Form (IPAQ-SF)

  Baseline and Week 8

Study Arms (2)

Morning Chronotype - Moderate-Intensity Resistance Exercise

EXPERIMENTAL

Participants identified as morning chronotypes (Munich Chronotype Questionnaire) will complete an 8-week, moderate-intensity resistance exercise program delivered online. Sessions are held in the morning, three times per week, lasting \~45 minutes (5-min warm-up, 35-min resistance training, 5-min cool-down). Exercises include push-ups, wall sits, squats, resistance band presses and pulls, rows, superman holds, and planks. Intensity is guided by 1RM testing, perceived exertion scales, and 7 point Likert scale of muscle soreness.

Behavioral: Moderate-Intensity Resistance Exercise Program

Evening Chronotype - Moderate-Intensity Resistance Exercise

EXPERIMENTAL

Participants identified as evening chronotypes (Munich Chronotype Questionnaire) will complete an 8-week, moderate-intensity resistance exercise program delivered online. Sessions are held in the morning, three times per week, lasting \~45 minutes (5-min warm-up, 35-min resistance training, 5-min cool-down). Exercises include push-ups, wall sits, squats, resistance band presses and pulls, rows, superman holds, and planks. Intensity is guided by 1RM testing, perceived exertion scales, and 7 point Likert scale of muscle soreness.

Behavioral: Moderate-Intensity Resistance Exercise Program

Interventions

Moderate-Intensity Resistance Exercise Program BEHAVIORAL

An 8-week, moderate-intensity resistance exercise program performed in the morning, 3 sessions/week on nonconsecutive days. Each 45-min session includes: 5-min warm-up (jumping jacks, high knees, running in place, hip hinge with reach, standing twists); 35-min progressive resistance training (Chest Press (Modified Push-Ups), Leg Press (Wall Sits with Squats), Squats, Shoulder Press (Resistance Band Overhead Press), Lat Pulldown (Resistance Band Pull-Downs), Rowing (Resistance Band Rows), Lower Back (Superman Holds), and Abdominals (Plank with Crunches)); and 5-min cool-down (Chest and Shoulder Stretch, Kneeling Hip Flexor Stretch, Standing Hamstring Stretch, Child's Pose with Side Stretch, and Cat-Cow Stretch ). Muscle soreness tracked after each session using 7-point Likert scale. Standardized videos, adherence checklists, resistance bands provided. Both chronotype groups complete identical sessions, outcomes compared.

Also known as: Telerehabilitation Exercise, Resistance Training, Exercise Intervention, Strength Training

Evening Chronotype - Moderate-Intensity Resistance Exercise; Morning Chronotype - Moderate-Intensity Resistance Exercise

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 18 and 35 years
• Generally healthy, with mild to moderate sleep disturbance as categorized by the Pittsburgh Sleep Quality Index (PSQI)
• Body Mass Index (BMI) \< 35 kg/m²
• No physical or organic limitations or diseases that would prevent participation in physical activity
• Non-smoker and non-alcoholic
• Caffeine consumption ≤ 2 cups per day (including coffee and energy drinks)
• Have not participated in more than 60 minutes/week of usual moderate-to-vigorous physical activity in the past 6 months, categorized as "moderate" on the International Physical Activity Questionnaire-Short Form (IPAQ-SF)
• No clinically diagnosed sleep apnea or other medical/psychiatric disorders responsible for sleep complaints
• Regular sleep schedule (no night shifts or transmeridian travel) in the 30 days prior to study enrollment
• Able to speak and write English

You may not qualify if:

• Current use of medications or psychotherapeutic drugs for insomnia or other psychiatric disorders
• Use of melatonin or other sleep aids in the past month
• Currently performing any aerobic or mind-body exercise classes (e.g., yoga, Pilates)
• Habitual daytime napping
• History of epilepsy or other convulsive disorders
• Pregnant individuals
• Habitual or recent use (within the past 30 days) of illegal drugs, psychotropic drugs, hypnotics, stimulants, or analgesics

Sponsors & Collaborators

• Medipol University: lead

Study Sites (1)

Medipol University

Istanbul, Beykoz/İstanbul, 34810, Turkey (Türkiye)

Location

Related Publications (20)

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  BACKGROUND

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Related Links

• National Sleep Foundation's sleep time duration recommendations: methodology and results summary
• Effects of resistance exercise training and stretching on chronic insomnia
• Resistance training improves sleep quality, redox balance and inflammatory profile in maintenance hemodialysis patients: a randomized controlled trial.

MeSH Terms

Conditions

Parasomnias; Sleep Initiation and Maintenance Disorders; Health Behavior; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Sleep Wake Disorders; Nervous System Diseases; Mental Disorders; Sleep Disorders, Intrinsic; Dyssomnias; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Gizem Ergezen Şahin, Dr. Assistant Professor

  Department of Physiotherapy and Rehabilitation/Istanbul Medipol University

  STUDY DIRECTOR

Central Study Contacts

Aliaa Salem Menshawi, PT, MSc (Cand.)

CONTACT

+905527304660; aliaamenshawi@gmail.com

Gehad Salem Menshawi, PT, MSc (Cand.)

CONTACT

+905524590178; j.menshawi@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Participants will not be masked due to the nature of the supervised exercise sessions and chronotype classification. Outcome measures rely on self-reported questionnaires and standardized assessments, making blinding of participants impractical.
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Participants will be randomized into two parallel groups based on chronotype classification (morning type or evening type). Both groups will complete the same 8-week, moderate-intensity resistance exercise program delivered via online sessions three times per week in the morning. Outcomes will be compared between the two chronotype groups to evaluate whether the effects of exercise on sleep quality and mood differ by chronotype.

Study Record Dates

• First Submitted: September 23, 2025
• First Posted: November 18, 2025
• Study Start: December 1, 2025
• Primary Completion: March 1, 2026
• Study Completion: May 1, 2026
• Last Updated: November 20, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)