NCT07524647

Brief Summary

Vertical jump performance is a determinant factor in physical performance, both in sports and in daily life and work activities. The muscular power of the lower limbs and the ability to generate explosive strength directly influence vertical jump performance and athletic success. For this reason, the vertical jump is widely used as a field test to evaluate performance capacity. Different strategies have been used to improve vertical jump performance, such as plyometric training (PT) and electrostimulation (EMS). PT consists of stretch-shortening cycle movements that involve high-intensity eccentric contractions followed by rapid and powerful concentric actions. EMS applies electrical current over muscles or peripheral nerves to generate involuntary muscle contractions. Both methods have shown significant effects in improving vertical jump height. In recent years, new therapeutic techniques have emerged in physiotherapy to improve neuromuscular recruitment and functionality, such as ultrasound-guided percutaneous neuromodulation (PNM-e). This technique consists of the electrical stimulation of a peripheral nerve or a motor point through a needle under ultrasound guidance, for therapeutic purposes. Evidence suggests that PNM-e can improve pain, functionality, balance, and muscle endurance, and increase muscle strength immediately after application. Specifically, low-frequency PNM-e applied to the femoral nerve has been shown to increase maximal quadriceps strength and vertical jump height in athletes. The femoral nerve plays a key role in quadriceps activation, a muscle group essential for knee extension and hip flexion, functions that are indispensable for both daily and sports activities. However, the specific effects of femoral nerve PNM-e on power and biomechanics of the vertical jump have not been sufficiently explored. Therefore, the main objective of this pilot study was to evaluate the effects of ultrasound-guided percutaneous neuromodulation of the femoral nerve on vertical jump performance. The secondary objective was to compare the effects of isolated plyometric training versus its combination with PNM-e to determine whether the combined approach offers additional benefits on jump performance. A randomized experimental study was carried out with healthy athletes who regularly practice sports. Participants were randomly assigned to a control group (two plyometric training sessions) or to an experimental group (two plyometric training + PNM-e interventions sessions); in both cases the sessions were separated by 7 days. Vertical jump performance was measured twice using the countermovement jump (CMJ) test (before the first session and after the second one). It is expected that ultrasound-guided percutaneous neuromodulation of the femoral nerve, combined with plyometric training, will produce greater improvements in jump performance due to enhanced quadriceps activation and neuromuscular efficiency.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
29

participants targeted

Target at below P25 for not_applicable

Timeline
1mo left

Started Jul 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress93%
Jul 2025Jun 2026

Study Start

First participant enrolled

July 8, 2025

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

April 6, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 13, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Last Updated

April 13, 2026

Status Verified

October 1, 2025

Enrollment Period

11 months

First QC Date

April 6, 2026

Last Update Submit

April 6, 2026

Conditions

Keywords

ultrasound-guided percutaneous neuromodulationinvasive physical therapyfemoral nervevertical jump

Outcome Measures

Primary Outcomes (1)

  • Vertical Jump Height

    Vertical jump height will be assessed using the MyJump2 app. This tool allows for precise measurement of jump height through video recording and frame-by-frame analysis. Each participant will perform ten maximum jumps in each measurement, and all results will be recorded. The evaluation will be carried out under standardized conditions, with participants dressed in athletic wear and after a warm-up.

    Baseline (pre-intervention) and post-intervention (after 1 week).

Secondary Outcomes (4)

  • Flight Time

    Baseline (pre-intervention) and post-intervention (after 1 week).

  • Force

    Baseline (pre-intervention) and post-intervention (after 1 week).

  • Movement Velocity

    Baseline (pre-intervention) and post-intervention (after 1 week).

  • Power

    Baseline (pre-intervention) and post-intervention (after 1 week).

Study Arms (2)

Plyometric Training

ACTIVE COMPARATOR
Behavioral: Plyometric Training

Femoral nerve NMP + Plyometric training

EXPERIMENTAL
Behavioral: Plyometric TrainingBehavioral: Bilateral femoral nerve ultrasound guide neuromodulation

Interventions

The plyometric training program used was the one described by Sankey et al. as an effective exercise program for improving vertical jump: * 2 sets of 10 tuck jumps. * 2 sets of 10 alternating leg bounds. * 2 sets of 15 two-footed bench hops. * 2 sets of 20 rim jumps. The rest time between sets was 60 seconds.

Femoral nerve NMP + Plyometric trainingPlyometric Training

Bilateral application of an asymmetric biphasic current to the femoral nerve with a frequency of 10 Hz and a pulse width of 240 µs. The intensity of the current was increased until a visible but painless motor response was achieved, using the 10-10-10 protocol (10 seconds of stimulation - 10 seconds of rest - 10 repetitions) described by MVClinic Institute. The current was applied using Physio Invasiva 2.0 ®, and Agupunt APS® needles were used, the length of which depended on the patient's anatomy, taking as a safety reference the measurement of the distance from the skin to the target tissue, estimating the size between 0.30 x 40 and 0.30 x 50 mm. Before needle insertion, the skin was cleansed with isopropyl alcohol and chlorhexidine, a clean skin antiseptic. After locating the femoral nerve in the femoral triangle using a General Electrics LOGIQ S7 ultrasound system, the needle was introduced using a long-axis approach, at a 45° angle to the skin, until it reached the epineurium of t

Femoral nerve NMP + Plyometric training

Eligibility Criteria

Age16 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Practice at least 6 hours of physical activity a week.

You may not qualify if:

  • Serious illnesses
  • Cardiovascular pathologies
  • Physical injuries that prevented them from participating in sports in the three months prior to the start of the study
  • Any absolute contraindication to invasive physical therapy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centro de Fisioterapia FyS

Narón, A Coruña, 15570, Spain

Location

MeSH Terms

Interventions

Plyometric Exercise

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Francisco Minaya Muñoz, Doctor

    CEU San Pablo University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Student at CEU San Pablo University

Study Record Dates

First Submitted

April 6, 2026

First Posted

April 13, 2026

Study Start

July 8, 2025

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

April 13, 2026

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared due to the nature of the study as a university master's project and the lack of a formal data sharing plan.

Locations