Biological Maturation and Plyometric Exercise
BiMaPlEx
The Effect of Biological Maturation on Indices of Exercise-induced Muscle Damage, Neuromuscular Fatigue and Performance After Acute Plyometric Exercise
1 other identifier
interventional
20
1 country
1
Brief Summary
Plyometric training comprises one of the most widely used training methods in both individual and team sports, and is widely used by coaches as one of the main training in both adults, and children. Plyometric training highly includes the component of eccentric contraction. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD), which is accompanied by increased delayed onset of muscle soreness (DOMS), inflammatory responses, increased levels of muscle proteins into the circulation, oxidative stress, and reduction of muscle function and performance the following days. Although plyometric training is widely used in children and may lead to EIMD, there is limited data regarding the acute effects of plyometric exercise training in children. Additionally, the effect of the biological maturation status of children on EIMD after acute plyometric exercise training has not been investigated. The aim of this study is to examine the effect of biological maturation on EIMD after acute plyometric exercise training in children.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2022
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 23, 2022
CompletedStudy Start
First participant enrolled
June 27, 2022
CompletedFirst Posted
Study publicly available on registry
July 5, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 30, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
July 30, 2022
CompletedNovember 4, 2022
November 1, 2022
1 month
June 23, 2022
November 3, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (11)
Changes in Creatine kinase
CK will be measured in plasma using a Clinical Chemistry Analyzer with commercially available kits.
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in blood lactate
Lactate will be measured in capillary blood with a hand-portable analyzer.
Baseline (pre), 4 minutes post-plyometric training
Changes in DOMS
DOMS of knee extensors and knee flexors of both lower extremities will be measured during palpation of the muscle belly and the distal region after performing three repetitions of a full squat and each participant will rate perceived soreness on a scale ranging from 1 (no soreness) to 10 (very sore).
Baseline (pre), post-, 24 hours post-, 48 hours post-, 72 hours postplyometric training
Changes in 10m sprint time
10m sprint time will be measured using light cells Chronojump system
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in 30m sprint time
30m sprint time will be measured using light cells Chronojump system
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in squat jump
Squat jump height will be measured using a Chronojump contact platform
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in counermovement jump
Counermovement jump height will be measured using a Chronojump contact platform
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in concentric peak torque
Concentric peak torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in eccentric peak torque
Eccentric peak torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer
Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in isometric peak torque
Isometric peak torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer
Baseline (pre), post-, 24 hours post-, 48 hours post-, 72 hours post-plyometric training
Changes in maximal voluntary isometric contraction (MVIC)
MVIC of knee extensors will be measured on an isokinetic dynamometer
Baseline (pre), post-, 1 hour post-, 2 hours post-, 3 hours post-plyometric training
Secondary Outcomes (10)
Biological maturation stage
Baseline
Testosterone levels
Baseline
Age from Peak Height Velocity (APHV)
Baseline
Body weight
Baseline
Body height
Baseline
- +5 more secondary outcomes
Study Arms (2)
Pre-adolescents
EXPERIMENTALAcute plyometric training
Adolescents
EXPERIMENTALAcute plyometric training
Interventions
Participants will perform: 8 sets of 10 maximal countermovement jumps
Eligibility Criteria
You may qualify if:
- Normal BMI
- No history of growth irregularities
- No musculoskeletal injuries for at least six months prior to the study
- No use of drugs or ergogenic supplements for at least one month prior to the study
- No participation at exercise with eccentric component for at least three days prior to the study
- No energy drinks consumption before each experimental trial
You may not qualify if:
- Abnormal BMI
- History of growth irregularities
- Musculoskeletal injuries in the last six months prior to the study
- Use of drugs or ergogenic supplements in the last month prior to the study
- Participation at exercise with eccentric component in the last three days prior to the study
- Energy drinks consumption before each experimental trial
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Physical Education and Sport Science, Uninersity of Thessaly
Trikala, Thessaly, 42100, Greece
Related Publications (3)
Marginson V, Rowlands AV, Gleeson NP, Eston RG. Comparison of the symptoms of exercise-induced muscle damage after an initial and repeated bout of plyometric exercise in men and boys. J Appl Physiol (1985). 2005 Sep;99(3):1174-81. doi: 10.1152/japplphysiol.01193.2004. Epub 2005 Apr 7.
PMID: 15817716BACKGROUNDDeli CK, Fatouros IG, Paschalis V, Georgakouli K, Zalavras A, Avloniti A, Koutedakis Y, Jamurtas AZ. A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys. Pediatr Exerc Sci. 2017 Aug;29(3):316-325. doi: 10.1123/pes.2016-0185. Epub 2017 Feb 6.
PMID: 28165870BACKGROUNDAsadi A, Ramirez-Campillo R, Arazi H, Saez de Villarreal E. The effects of maturation on jumping ability and sprint adaptations to plyometric training in youth soccer players. J Sports Sci. 2018 Nov;36(21):2405-2411. doi: 10.1080/02640414.2018.1459151. Epub 2018 Apr 3.
PMID: 29611771BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Chariklia K Deli, PhD
University of Thessaly
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
June 23, 2022
First Posted
July 5, 2022
Study Start
June 27, 2022
Primary Completion
July 30, 2022
Study Completion
July 30, 2022
Last Updated
November 4, 2022
Record last verified: 2022-11