NCT07434297

Brief Summary

a comparative study to evaluate the pontic site soft tissue augmentation by partially de-epithelized connective tissue graft versus completely de-epithelized connective tissue graft (both grafts harvested from the hard palate). pontic site soft tissue augmentation allows the correction of soft tissue to allow proper fixed dental bridge fabrication (for esthetic and functional purposes)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 20, 2024

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 12, 2026

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 2, 2026

Completed
23 days until next milestone

First Posted

Study publicly available on registry

February 25, 2026

Completed
Last Updated

February 25, 2026

Status Verified

January 1, 2025

Enrollment Period

1.1 years

First QC Date

January 12, 2026

Last Update Submit

February 19, 2026

Conditions

Soft Tissue AugmentationPontic Site Development

Outcome Measures

Primary Outcomes (1)

  • keratinized tissue thickness

    time of enrollment, 3 and 6 months postoperative

Secondary Outcomes (2)

  • soft tissue healing index

    6 months postoperative

  • Pain score

    3 and 7 days postoperative

Study Arms (2)

intervention (using autogenous de-epithelized connective tissue graft for pontic site)

OTHER

intervention (using autogenous de-epithelized connective tissue graft for pontic site soft tissue augmentation

Procedure: Intervention

control group ( partially De-Epithelized connective tissue graft )

OTHER

control group ( partially autogenous De-Epithelized connective tissue graft )

Procedure: Control

Interventions

InterventionPROCEDURE

de-epithelized connective tissue graft for soft tissue augmentation for pontic site development

intervention (using autogenous de-epithelized connective tissue graft for pontic site)
ControlPROCEDURE

partially de-epithelized connective tissue graft for soft tissue grafting for pontic site development

control group ( partially De-Epithelized connective tissue graft )

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age 20-45 years
  • medically free
  • bounded missing teeth
  • patient accepting the fixed prosthetics as a treatment option
  • restorable adjacent abutments
  • periodontally healthy adjacent abutments
  • motivated patient to have the treatment
  • bleeding and plaque index less than 20%

You may not qualify if:

  • systemic diseases
  • smoking
  • pregnancy
  • patients with pervious soft tissue grafting

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Modern Sciences and Arts University

Giza, Egypt

Location

MeSH Terms

Interventions

Methods

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2026

First Posted

February 25, 2026

Study Start

December 20, 2024

Primary Completion

February 1, 2026

Study Completion

February 2, 2026

Last Updated

February 25, 2026

Record last verified: 2025-01

Locations

EG(1)