NCT07351097

Brief Summary

This study will try to answer the following question: Will adding mini-squat exercises at different angles (30°,45°, and 60°) to leg press exercise influence quadriceps and hamstring strength and H:Q angle in football players?

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 2, 2025

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

December 31, 2025

Completed
20 days until next milestone

First Posted

Study publicly available on registry

January 20, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 3, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 3, 2026

Completed
Last Updated

March 27, 2026

Status Verified

January 1, 2026

Enrollment Period

6 months

First QC Date

December 31, 2025

Last Update Submit

March 25, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Measurement of quadriceps strength

    * The participant will be seated on the isokinetic dynamometer chair, with proper posture and alignment ensured. * The lateral femoral epicondyle (the anatomical axis of the knee joint) will be aligned with the mechanical axis of the dynamometer arm. * The lever arm of the dynamometer will be securely attached to the participant's lower leg, just above the ankle, using a padded cuff. * The participant will be instructed to perform maximal knee extension against the resistance of the device, moving from a flexed to an extended position. * The test will be conducted unilaterally, assessing one leg at a time. * The participant will be encouraged to exert maximal effort during each repetition. * The isokinetic device will record key outcome measures including peak torque (Nm), average power, and total work for each repetition. These values will be used to quantify quadriceps strength.

    1.5 months

  • Measurement of hamstrings muscle strength

    All previously described quadriceps muscle evaluation procedures will be applied for the hamstrings muscle strength test; however, the range of motion will be set from full knee extension, and the participant will be instructed to actively bend the knee against the resistance of the device to 90°

    1.5 months

  • Hamstring to quadriceps H:Q ratio calculation

    The H-Q ratio refers to the relative strength of the hamstring muscles compared to the quadriceps, typically measured under isokinetic conditions (at the same angular velocity). It is calculated as the maximal concentric knee flexion strength divided by maximal concentric knee extension strength.

    1.5 months

Study Arms (4)

Group A (mini-squat at 30° knee flexion and leg press)

EXPERIMENTAL

Fifteen participants will receive mini-squat exercises at 30° knee flexion and leg press exercises

Procedure: mini-squat exercises at 30°

Group B (mini-squat at 45° knee flexion and leg press)

ACTIVE COMPARATOR

Fifteen participants will receive mini-squat exercises at 45° knee flexion and leg press exercises

Procedure: mini-squat exercises at 45°

Group C (mini-squat at 60° knee flexion and leg press)

ACTIVE COMPARATOR

Fifteen participants will receive mini-squat exercises at 60°and leg press exercises

Procedure: mini-squat exercises at 60°

Group D (Control group: leg press exercise program only)

PLACEBO COMPARATOR

Fifteen participants will receive leg press exercise program only.

Procedure: leg press exercise

Interventions

mini-squat exercises at 45° knee flexion and leg press exercises

Group B (mini-squat at 45° knee flexion and leg press)

mini-squat exercises at 60°and leg press exercises

Group C (mini-squat at 60° knee flexion and leg press)

leg press exercise program only

Group D (Control group: leg press exercise program only)

mini-squat exercises at 30° knee flexion and leg press exercises

Group A (mini-squat at 30° knee flexion and leg press)

Eligibility Criteria

Age18 Years - 30 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsMale football players aged between 18-30 years
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male football players aged between 18-30 years (Scoz et al., 2021).
  • Body Mass Index (BMI) between 18.5 and 24.9 kg/m² (Walsh et al., 2018 \& Sattar\& Lean, 2009).
  • Currently training or playing with a registered football club/team.
  • Hamstring-to-Quadriceps (HQ) strength ratio of ≥ 0.6 (Çelebi et al., 2018).
  • Having no oral or injectable non-steroidal anti-inflammatory drugs (NSAID), 2weeks before starting study.
  • Having no oral injectable corticosteroids 3 months before starting the study.

You may not qualify if:

  • History of acute or chronic injury to the knee, hip, or ankle joint
  • Undergoing any other rehabilitation or physical therapy programs during the six weeks before starting the study
  • Diagnosed with neurological or systemic disorders affecting muscle function or balance
  • Participation in competitive sports or high-intensity training outside the study protocol during the study period
  • Presence of any contraindication to exercise, such as uncontrolled hypertension or heart conditions.
  • Clinically free from lower limb injuries.
  • Having no history of neurological, cardiovascular, or musculoskeletal disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jazan University Hospital

Jizan, Saudi Arabia

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Prof.Dr.Nasr Abdelkader

    Cairo Univesity

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof

Study Record Dates

First Submitted

December 31, 2025

First Posted

January 20, 2026

Study Start

September 2, 2025

Primary Completion

March 3, 2026

Study Completion

March 3, 2026

Last Updated

March 27, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations