Exercise-induced Hypoalgesia and Proprioceptive Changes, Comparing Isometric to Isotonic Neck Exercises

NCT06465394 | Recruiting

• 1 other identifier: IRB-24-100
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Exercised induced hypoalgesia (EIH) (reduction in pain) after exercise has been studied in the literature, but no comparisons have been made specifically looking at different types of exercise (isometric/dynamic moving through a range of motion with resistance versus isotonic/applying static resistance to a joint not moving) with neck muscle strengthening. This study will explore to see if one form of exercise is superior to the other in providing EIH. Another benefit of exercise is improving proprioception (knowing where our body is in space). Again no specific investigation has been done comparing isometric versus isotonic exercises for neck muscles. Both of these exercises are often prescribed in physical therapy so further understanding the benefits of them can help improve the prescription of exercises for patients.

Conditions

Exercise

Outcome Measures

Primary Outcomes (1)

• PPT

  Pain Pressure Threshold with use of algometer

  Pre post measure before and after exercise session taking approximately 10 minutes

Secondary Outcomes (1)

• JPE

  Pre post measure before and after exercise session taking approximately 10 minutes

Study Arms (2)

Isometric Exercise

ACTIVE COMPARATOR

Isometric test protocol. Participants will be asked to perform the exercise at a moderate exercise level (3/10 on the mRPE scale provided to them). They will complete a 1, 10-second isometric hold to their hand dominant side (if ambidextrous, the side the participant would report as the most dominant side) to allow them to find their "moderate" intensity level. The participant will then take a 2-minute rest before beginning the exercise routine and will be instructed to keep a consistent resistance level during the exercise bout. During the exercise, the subjects will hold the rotation contraction for 10 seconds, take a 2-second rest, complete this 5 times, and then change to the left side. They will do this for 3 sets of right and left. Researchers will time the exercises and give verbal instructions to make sure they are performing for the appropriate amount of time and rest periods.

Procedure: Exercise

Isotonic Exercise

ACTIVE COMPARATOR

The resistance level will stay at the participant's selected moderate level during the entire testing unless they need to stop due to pain or difficulty completing the exercise. During the exercise, the participants will be rotating to the right first at a pace of 1 second for concentric contraction to full rotation and 1 second for eccentric contraction, returning the head to the neutral position. The participant will continue this pace to complete 5 repetitions and then take a 2-second rest before continuing this sequence 5 times (a total of 25 reps) before switching and doing left rotation in the same fashion. This will be done for a total of 3 sets for both right and left rotation. The use of a metronome will be used along with the researcher's verbal instructions and cueing to maintain the proper sequence and timing of the exercise.

Procedure: Exercise

Interventions

Exercise PROCEDURE

Neck exercises in a cross over design that the participants will do both types of interventions with a washout period inbetween.

Isometric Exercise; Isotonic Exercise

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• years old,
• all genders,
• healthy individuals with no neck pain

You may not qualify if:

• Medical restrictions to physical activity
• History of chronic pain (pain \> 3 months) or current acute neck pain
• Unable to refrain from alcohol, pain medications, and vigorous exercise 24 hours prior to testing

Sponsors & Collaborators

• University of South Dakota: lead

Study Sites (1)

University of South Dakota

Vermillion, South Dakota, 57069, United States

RECRUITING

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Kory J Zimney, PhD

  University of South Dakota

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Kory J Zimney, PhD

CONTACT

6056586373; kory.zimney@usd.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 10, 2024
• First Posted: June 18, 2024
• Study Start: August 12, 2024
• Primary Completion: December 20, 2024
• Study Completion: May 5, 2025
• Last Updated: December 6, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)