Acute Effects of Three Different Types Single Leg Exercise in Copd

NCT06466213 | Completed

• 1 other identifier: GO23-193
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and muscle oxygenation are observed in COPD. One leg exercise result is not enough to highlight these parameters.

Conditions

Exercise

Outcome Measures

Primary Outcomes (1)

• six minute walk test

  six minute walk test in meter

  beginning, day 1

Secondary Outcomes (10)

• cardiopulmonary exercise test

  beginning, day 2

• single leg extremity test

  beginning, day 3

• lung function

  beginning, day 1

• muscle strength (isometric)

  beginning day 1

• muscle strength (10 repeated max)

  beginning, day 1

Study Arms (1)

single session one leg exercise intervantion in COPD

EXPERIMENTAL

first session: single session leg Continuous exercise intervantion will be applied to COPD. Unilaterally single leg continuous exercise will be performed as only one session second session : single session leg high intensity interval exercise intervantion will be applied to COPD. Unilaterally single leg hııt exercise will be performed as only one session third sessionsingle session leg resistance exercise intervantion will be applied to COPD. Respirocally leg strength (knee extantion ) exercise will be performed

Other: single exercise bout about one-leg exercise

Interventions

single exercise bout about one-leg exercise OTHER

cycle exercise includes single leg

single session one leg exercise intervantion in COPD

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• COPD patients that applied to physiotherapy
• cooperate to test
• no severe ortopedical and neurological disease no severe cardiovascular disease volunteer to study

You may not qualify if:

• have an acute exacerbation
• hypoxemia \[PaO2\] \<55 mmHg
• no cooperated to test no volunteer to study having ortophedical and neurological diesase that affecting of tests having severe cardiovascular disease

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Elif Kocaaga

Ankara, Ankara, Turkey (Türkiye)

Location

Related Publications (1)

• Evans RA, Dolmage TE, Mangovski-Alzamora S, Romano J, O'Brien L, Brooks D, Goldstein RS. One-Legged Cycle Training for Chronic Obstructive Pulmonary Disease. A Pragmatic Study of Implementation to Pulmonary Rehabilitation. Ann Am Thorac Soc. 2015 Oct;12(10):1490-7. doi: 10.1513/AnnalsATS.201504-231OC.

  PMID: 26291542 BACKGROUND

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• elif kocaaga, ms

  Hacettepe University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: May 17, 2024
• First Posted: June 20, 2024
• Study Start: February 20, 2024
• Primary Completion: March 28, 2025
• Study Completion: March 28, 2025
• Last Updated: December 4, 2025

Record last verified: 2025-11

Locations

TU (1)